Efficacy of Cut-and-Sew Box Isolation of the Posterior Left Atrium for Treatment of Atrial Fibrillation—Long-term Follow-up after a Modified Maze Procedure

Authors

  • Roman Laszlo
  • Hanna Graze
  • Christian Haas
  • Klaus Kettering
  • Hermann Aebert
  • Gerhard Ziemer
  • Meinrad Gawaz
  • Jürgen Schreieck

DOI:

https://doi.org/10.1532/HSF98.20111105

Abstract

Background: Box isolation of the posterior left atrium is one surgical or catheter ablative approach for treating atrial fibrillation (AF). In such cases, incomplete transmurality or recovery of pulmonary vein conduction after the application of various ablative techniques is considered the main reason for the recurrence of postprocedural arrhythmia. The use of solely cut-and-sew box isolation does not have these disadvantages and therefore demonstrates maximum efficacy for this therapeutic approach.

Methods: We treated 15 patients with both an indication for open heart surgery and AF (2 paroxysmal, 6 short persistent [<12 months], and 7 long persistent [>12 months] cases) with a solely cut-and-sew box lesion. These patients were then retrospectively followed up over the long term with respect to the end point of freedom of atrial tachyarrhythmias >30 seconds.

Results: The median follow-up duration was 42 months (range, 32-84 months). Five (63%) of 8 patients with preoperative paroxysmal or short persistent AF had no arrhythmia recurrence, whereas arrhythmia recurrence was documented in all 7 patients with preoperative long persistent AF.

Conclusions: Despite reliable transmural isolation with cut-and-sew lesions, we observed long-term arrhythmia recurrence in patients who had preoperative paroxysmal or short persistent AF, suggesting that therapy approaches that are more complex than box isolation might be needed for selected patients to achieve long-term stable sinus rhythm, despite the initially paroxysmal or short persistent character of the arrhythmia. A high rate of recurrence in patients with severe structural heart disease and preoperative long persistent AF might indicate that, in general, isolation of the left posterior atrium alone is not an adequate therapeutic approach for these patients.

References

Bazaz R, Nosbisch J, Schwartzman D. 2003. Insights gained into form and function of the posterior left atrium. Pacing Clin Electrophysiol 26:1386-406.nCalkins H, Brugada J, Packer DL, et al. 2007. HRS/EHRA/ECAS expert Consensus Statement on catheter and surgical ablation of atrial fibrillation: recommendations for personnel, policy, procedures and follow-up. A report of the Heart Rhythm Society (HRS) Task Force on catheter and surgical ablation of atrial fibrillation. Heart Rhythm 4:816-61.nDeneke T, Khargi K, Müller KM, et al. 2005. Histopathology of intraoperatively induced linear radiofrequency ablation lesions in patients with chronic atrial fibrillation. Eur Heart J 26:1797-803.nErnst S, Schlüter M, Ouyang F, et al. 1999. Modification of the substrate for maintenance of idiopathic human atrial fibrillation: efficacy of radiofrequency ablation using nonfluoroscopic catheter guidance. Circulation 100:2085-92.nGage BF, Waterman AD, Shannon W, Boechler M, Rich MW, Radford MJ. 2001. Validation of clinical classification schemes for predicting stroke: results from the National Registry of Atrial Fibrillation. JAMA 285:2864-70.nGuiraudon GM, Jones DL, Skanes AC, et al. 2005. En bloc exclusion of the pulmonary vein region in the pig using off pump, beating, intra-cardiac surgery: a pilot study of minimally invasive surgery for atrial fibrillation. Ann Thorac Surg 80:1417-23.nHanda N, Schaff HV, Morris JJ, Anderson BJ, Kopecky SL, Enriquez-Sarano M. 1999. Outcome of valve repair and the Cox maze procedure for mitral regurgitation and associated atrial fibrillation. J Thorac Cardiovasc Surg 118:628-35.nKamino K. 1991. Optical approaches to ontogeny of electrical activity and related functional organization during early heart development. Physiol Rev 71:53-91.nKumagai K, Muraoka S, Mitsutake C, Takashima H, Nakashima H. 2007. A new approach for complete isolation of the posterior left atrium including pulmonary veins for atrial fibrillation. J Cardiovasc Electrophysiol 18:1047-52.nLim TW, Koay CH, McCall R, See VA, Ross DL, Thomas SP. 2008. Atrial arrhythmias after single-ring isolation of the posterior left atrium and pulmonary veins for atrial fibrillation: mechanisms and management. Circ Arrhythm Electrophysiol 1:120-6.nMandapati R, Skanes A, Chen J, Berenfeld O, Jalife J. 2000. Stable microreentrant sources as a mechanism of atrial fibrillation in the isolated sheep heart. Circulation 101:194-9.nMorillo CA, Klein GJ, Jones DL, Guiraudon CM. 1995. Chronic rapid atrial pacing. Structural, functional, and electrophysiological characteristics of a new model of sustained atrial fibrillation. Circulation 91:1588-95.nNdrepepa G, Weber S, Karch MR, et al. 2002. Electrophysiologic characteristics of the spontaneous onset and termination of atrial fibrillation. Am J Cardiol 90:1215-20.nOuyang F, Antz M, Ernst S, et al. 2005. Recovered pulmonary vein conduction as a dominant factor for recurrent atrial tachyarrhythmias after complete circular isolation of the pulmonary veins: lessons from double Lasso technique. Circulation 111:127-35.nPruitt JC, Lazzara RR, Ebra G. 2007. Minimally invasive surgical ablation of atrial fibrillation: the thoracoscopic box lesion approach. J Interv Card Electrophysiol 20:83-7.nReddy VY, Neuzil P, D'Avila A, Ruskin JN. 2008. Isolating the posterior left atrium and pulmonary veins with a "box" lesion set: use of epicardial ablation to complete electrical isolation. J Cardiovasc Electrophysiol 19:326-9.nSanders P, Hocini M, Jais P, et al. 2007. Complete isolation of the pulmonary veins and posterior left atrium in chronic atrial fibrillation. Long-term clinical outcome. Eur Heart J 28:1862-71.nSohara H, Takeda H, Ueno H, Oda T, Satake S. 2009. Feasibility of the radiofrequency hot balloon catheter for isolation of the posterior left atrium and pulmonary veins for the treatment of atrial fibrillation. Circ Arrhythm Electrophysiol 2:225-32.nSueda T, Nagata H, Orihashi K, et al. 1997. Efficacy of a simple left atrial procedure for chronic atrial fibrillation in mitral valve operations. Ann Thorac Surg 63:1070-5.nTamborero D, Mont L, Berruezo A, et al. 2009. Left atrial posterior wall isolation does not improve the outcome of circumferential pulmonary vein ablation for atrial fibrillation: a prospective randomized study. Circ Arrhythm Electrophysiol 2:35-40.nThomas SP, Lim TW, McCall R, Seow SC, Ross DL. 2007. Electrical isolation of the posterior left atrial wall and pulmonary veins for atrial fibrillation: feasibility of and rationale for a single-ring approach. Heart Rhythm 4:722-30.nTodd DM, Skanes AC, Guiraudon G, et al. 2003. Role of the posterior left atrium and pulmonary veins in human lone atrial fibrillation: electrophysiological and pathological data from patients undergoing atrial fibrillation surgery. Circulation 108:3108-14.nVoeller RK, Bailey MS, Zierer A, et al. 2008. Isolating the entire posterior left atrium improves surgical outcomes after the Cox maze procedure. J Thorac Cardiovasc Surg 135:870-7.nWong JW, Mak KH. 2006. Impact of maze and concomitant mitral valve surgery on clinical outcomes. Ann Thorac Surg 82:1938-47.nYamaguchi Y, Kumagai K, Nakashima H, Saku K. 2010. Long-term effects of box isolation on sympathovagal balance in atrial fibrillation. Circ J 74:1096-103.n

Published

2012-02-23

How to Cite

Laszlo, R., Graze, H., Haas, C., Kettering, K., Aebert, H., Ziemer, G., Gawaz, M., & Schreieck, J. (2012). Efficacy of Cut-and-Sew Box Isolation of the Posterior Left Atrium for Treatment of Atrial Fibrillation—Long-term Follow-up after a Modified Maze Procedure. The Heart Surgery Forum, 15(1), E28-E33. https://doi.org/10.1532/HSF98.20111105

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