Effects of Coronary Artery Bypass Grafting Surgery on Olfactory and Taste Functions

  • Kemalettin Erdem Department of Cardiovascular Surgery, Faculty of Medicine, Bolu Abant Izzet Baysal University, Bolu, Turkey
  • Erhan Renan Ucaroglu Department of Cardiovascular Surgery, Faculty of Medicine, Bolu Abant Izzet Baysal University, Bolu, Turkey
  • Abidin Sehitogullari Departmant of Thoracic Surgery, Faculty of Medicine, Sakarya University, Sakarya, Turkey
  • Ahmet Yuksel Department of Cardiovascular Surgery, Faculty of Medicine, Bolu Abant Izzet Baysal University, Bolu, Turkey
  • Hikmet Tekce Department of Nephrology, Faculty of Medicine, Bolu Abant Izzet Baysal University, Bolu, Turkey
  • Yusuf Velioglu Department of Cardiovascular Surgery, Faculty of Medicine, Bolu Abant Izzet Baysal University, Bolu, Turkey
  • Abdullah Demirhan Department of Anesthesiology and Reanimation, Faculty of Medicine, Bolu Abant Izzet Baysal University, Bolu, Turkey
  • Ufuk Turan Kursat Korkmaz Department of Cardiovascular Surgery, Faculty of Medicine, Bolu Abant Izzet Baysal University, Bolu, Turkey
  • Ferhat Borulu Department of Cardiovascular Surgery, Faculty of Medicine, Ataturk University, Erzurum, Turkey
  • Osman Unal Department of Cardiovascular Surgery, Faculty of Medicine, Bolu Abant Izzet Baysal University, Bolu, Turkey
  • Aynur Ulku Department of Cardiovascular Surgery, Faculty of Medicine, Bolu Abant Izzet Baysal University, Bolu, Turkey
  • Ebru Calisir Department of Cardiovascular Surgery, Faculty of Medicine, Bolu Abant Izzet Baysal University, Bolu, Turkey
Keywords: Coronary artery bypass grafting, olfactory, taste

Abstract

Background: Olfactory and taste sensations have a high impact on the quality of life. Impaired olfactory and taste functions may have a negative effect on physical and mental well-being, personal hygiene, and nutritional satisfaction, leading to the occurrence of depressive symptoms and impaired quality of life. Therefore, the recovery period of patients with disturbed olfactory and taste functions may be prolonged, and return to active life may be delayed. We designed this study to determine whether on-pump and off-pump coronary artery bypass grafting (CABG) surgeries have any effects on olfactory and taste functions and compare these functions between the surgical groups.

Methods: A total of 60 patients, who underwent elective isolated first-time CABG, were included in this study. Patients were divided into two groups as Off-Pump and On-Pump CABG groups with 30 patients in each group. In addition to patients' primary clinical and laboratory data, olfactory and taste functions were evaluated pre- and postoperatively in both groups separately, and then these functions were compared between the groups. Olfactory functions were evaluated by the Brief Smell Identification Test, while taste functions by the Burghart Taste test.

Results: Olfactory functions significantly were disrupted in the postoperative period in patients undergoing on-pump CABG (P value < .05), while these functions significantly were not affected in patients undergoing off-pump CABG (P value > .05). During the preoperative period, advanced age and smoking were detected to be independent predictors of impaired olfactory function for the study population. During the postoperative period, smoking, amount of postoperative bleeding and serum low-density lipoprotein (LDL) level were found to be independent predictors of impaired olfactory function for just the On-Pump CABG Group. In both groups, no significant deterioration in taste functions occurred during the postoperative period (P value > .05).

Conclusion: Our study demonstrated that olfactory function was impaired in patients, who underwent on-pump CABG in the postoperative period, and significant impairment in taste function was present in neither off-pump nor on-pump CABG patients. However, the results of our study should be supported by more comprehensive, prospective, randomized controlled trials with more extensive patient series and by further tests.

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Published
2019-10-01
How to Cite
Erdem, K., Ucaroglu, E., Sehitogullari, A., Yuksel, A., Tekce, H., Velioglu, Y., Demirhan, A., Korkmaz, U., Borulu, F., Unal, O., Ulku, A., & Calisir, E. (2019). Effects of Coronary Artery Bypass Grafting Surgery on Olfactory and Taste Functions. The Heart Surgery Forum, 22(5), E416-E422. https://doi.org/10.1532/hsf.2505
Section
Articles