Dysfunction of Left Ventricle as an Indication for Off-Pump Coronary Artery Bypass Grafting
DOI:
https://doi.org/10.1532/hsf.915Abstract
Background: Coronary artery bypass grafting (CABG) with cardiopulmonary bypass carries significant risk for patients with severe left ventricular (LV) dysfunction.
Methods: Between 1997 and 2000, 240 patients underwent OPCAB. The patients were retrospectively divided into 2 groups with regard to LV function. Group 1 consisted of 90 patients with ejection fraction (EF) < 35% and group 2 of 150 patients without severe LV impairment and EF > 35%. Patients were compared for preoperative risk factors, perioperative mortality, and postoperative complications.
Results: Preoperative expected mortality according to EuroSCORE was higher in group 1, 5.95, compared with group 2, 2.66 (P = .0005). A few preoperative risk factors were more common in group 1: urgent operation (P = .00001), unstable angina (P = .0018), Canadian Cardiovascular Society class (P = .001), myocardial infarction (P = .0001), and peripheral arteriopathy (P = .0006). Mean number of grafts was 1.51 in group 1 and 1.55 in group 2 with the same internal thoracic artery utilization. Perioperative drainage, anesthesia and intubation time, transfusion rate, and use of inotropes were comparable. Actual, nonadjusted mortality was 2.5% in group 1 and 1.4% in group 2 (P = not significant). Overall rates of postoperative complications were comparable; only use of an intraoperative balloon pump was more frequent in group 1 (P = .006). Postoperative stay was shorter in group 1 (P = .007).
Conclusions: Off-pump CABG for patients with LV impairment is associated with surgical outcome similar to that among patients with normal LV function, in spite of
References
Akins CW, Bouchar C, Pohost G. 1984. Preservation of IVS function in patients having CABG without CPB. Tex Heart Inst J 11:52-7.nLoop F, Lytle B, Cosgrove DM, et al. 1986. Influence of the internal mammary artery graft on 10 years survival and other cardiac events. N Engl J Med 314:1-6.nMoshkowitz Y, Sternik L, Paz Y, et al. 1997. Primary CABG without CPB in impaired LV function. Ann Thorac Surg 63:S44-7.nO'Connor GT, Plume SK, Olmstead EM, et al. 1992. Multivariate prediction of in hospital mortality associated with CABG surgery. Circulation 85:2110-8.nPfister A, Zaki M, Garcia J. 1992. CABG without CPB. Ann Thorac Surg 54:1085-92.nArom KV, Flavin TF, Emery RW, Kshettry VR, Petersen RJ, Janey PA. 2000. Is low ejection fraction safe for off-pump coronary bypass operation? Ann Thorac Surg 70:1021-5.nBolling S, Pagani F, Deeb G, et al. 1998. Intermediate-term outcome of mitral reconstruction in cardiomyopathy. J Thorac Cardiovasc Surg 115:381-8.nBrasil L, Gomes W, Salomao R, et al. 1998. Inflammatory response after myocardial revascularization with or without CPB. Ann Thorac Surg 66:56-60.nChristakis GT, Weisel RD, Fremes SE, et al. 1992. CABG in patients with poor ventricular function. J Thorac Cardiovasc Surg 103:1083-92.nDell-Rizzo, Boyd D, Novick R, et al. 1998. Safety and cost-effectiveness of MIDCABG in high risk CABG. Ann Thorac Surg 66:1002-7.nKirklin JW, Barratt-Boys BG. 1993. Cardiac Surgery, 2nd ed. New York: Churchill Livingstone. p 83-97.n