Sutureless Robot-Assisted Mitral Valve Repair: An Animal Model

Authors

  • Clifton C. Reade
  • Curtis E. Bower
  • David M. Maziarz
  • Anne M. Conquest
  • You Su Sun
  • L. Wiley Nifong
  • W. Randolph Chitwood Jr

DOI:

https://doi.org/10.1532/hsf.652

Abstract

Background: Robotic mitral valve repair with the da Vinci robotic surgical system has been performed in more than 70 patients at our institution. This procedure reduces the need for blood transfusions, shortens hospital stay, and hastens return to normal activities. However, the robot-assisted repair also requires longer cardiopulmonary bypass and arrested-heart times than conventional open repairs. Because of increased risk of myocardial damage, arrhythmia, and other significant morbidities associated with longer arrested-heart time, a more efficient tissue approximation and adherence technique was evaluated to reduce operating time.

Methods: Twelve Dorset sheep were divided equally into 2 groups. In the control group Cosgrove-Edwards annuloplasty bands were secured to the posterior annulus with conventional 2-0 Ticron mattress sutures placed with robotic assistance. In the experimental group, the band was secured with double-armed nitinol U-clips placed with robotic assistance. Postoperative echocardiography was used to assess mitral valve function, and the animals were sacrificed at 3 or 6 months for histological evaluation.

Results: Total U-clip placement time was significantly decreased at 2.6 ± 0.2 (mean ± SEM) minutes versus total suture placement time at 4.9 ± 0.4 minutes (P = .001). The main difference in time occurred between clip deployment at 0.75 ± 0.1 minutes and suture tying at 2.78 ± 0.2 minutes (P = .000003). Pathologic review showed excellent band incorporation at 3 and 6 months. Echocardiographic imaging showed no discernible mitral valve stenosis or regurgitation. Conclusions: With more cardiac procedures progressing toward minimally invasive approaches, novel technology to improve existing techniques must be evaluated. Nitinol U-clips help to reduce arrested-heart time and may improve outcome by decreasing morbidity. U-clip placement is intuitive, easily learned, and effective in securing the annuloplasty band to the mitral annulus.

References

Buckberg GD, Olinger GN, Mulder DG, Maloney JV. 1975. Depressed postoperative cardiac performance: prevention by adequate myocardial protection during cardiopulmonary bypass. J Thorac Cardiovasc Surg 70:974-88.nFelger JE, Chitwood WR Jr, Nifong LW, Holbert D. 2001. Evolution of mitral valve surgery: toward a totally endoscopic approach. Ann Thorac Surg 72:1203-9.nNelson RL, McConnell DH, Goldstein SM, Maloney JV, Buckberg GD. 1975. The effects of profound topical cardiac hypothermia on myocardial blood flow, metabolism, compliance and function. Surg Forum 26:261-2.nNifong LW, Chu VF, Bailey BM, et al. 2003. Robotic mitral valve repair: experience with the da Vinci system. Ann Thorac Surg 75:438-43.n[NIH] National Institutes of Health (US). 1985. Guide for the care and use of laboratory animals. Bethesda (MD): NIH Publication No. 86-23.n

Published

2005-02-07

How to Cite

Reade, C. C., Bower, C. E., Maziarz, D. M., Conquest, A. M., Sun, Y. S., Nifong, L. W., & Jr, W. R. C. (2005). Sutureless Robot-Assisted Mitral Valve Repair: An Animal Model. The Heart Surgery Forum, 6(4), 254-257. https://doi.org/10.1532/hsf.652

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