Operative Mortality after Valvular Reoperations
DOI:
https://doi.org/10.1532/HSF98.20041154Abstract
Background: To determine the incidence and risk factors of mortality and morbidity in valvular reoperations.
Methods: Between January 1993 and December 2003, 309 valvular reoperations were performed. The reasons for reoperations were reconstructive surgery in first operation (110 patients, 35.5%), prosthetic valve endocarditis (12 patients, 3.8%), periprosthetic leakage (32 patients, 10.3%), new valve degenerations (12 patients, 3.8%), bioprosthetic dysfunction (92 patients, 29.7%), acute thrombotic stuck valve (30 patients, 9.7%), and pannus formation (21 patients, 6.7%). Mitral valves were replaced in 235 patients, aortic valves were replaced in 32 patients, 24 patients had aortic and mitral valve replacements, 2 patients had mitral and tricuspid valve replacements, and reconstruction of periprosthetic leakage was held in 16 patients. 264 patients had elective surgery, whereas 45 were operated on emergeny basis.
Results: Hospital mortality was 14.23%. Mortality rate was found to be 10.6% for elective cases and 35.5% for emergency cases. Permanent pacemaker was required in 12 patients, 3 patients had cerebrovascular events, and mediastinitis was observed in 1 patient. Multivariate analysis demonstrated that age >60 (P = .006; OR 7.3, 95% CI 1.7-30.1), emergency surgery (P = .001; OR 8.1, 95% CI 2.4-27.7), preoperative cerebrovascular accident (P = .003; OR 11.8, 95% CI 2.458.7), and concomitant ascending aorta replacement (P < .001; OR 27.4, 95% CI 6-127) were independent risk factors.
Conclusion: Valvular reoperations can be carried out with acceptable morbidity and mortality in elective operations but mortality rates are still very high in emergent cases.
References
Antunes MJ. 1992. Reoperations on cardiac valves. J Heart Valve Dis 1:15-28.nAkins CW, Buckley MJ, Daggett WM, et al. 1998. Risk of reoperative valve replacement for failed mitral and aortic bioprosthesis. AnnThorac Surg 65:1545-52.nJones JM, O'Kane H, Gladstone DJ, et al. 2001. Repeat heart valve surgery: Risk factors for operative mortality. J Thorac Cardiovasc Surg 122:913-8.nPansini S, Ottino G, Forsennati PG, et al. 1990. Reoperations on heart valve prosthesis: an analysis of operative risks and late results. Ann Tho-rac Surg 50:590-6.nPihler JM, Blackstone EH, Bailey KR, et al. 1995. Reoperation on prosthetic heart valves. J Thorac Cardiovasc Surg 109:30-48.nBrando CMA, Pomerantzeft PMA, Souza LR, et al. 2002. Multivariate analysis of risk factors for hospital mortality in valvular reoperations for prosthetic valve dysfunction. Eur J Cardiothorac Surg 22:922-6.nCohn LH, Aranki SF, Rizzo RJ, et al. 1993. Decrease in operative risk of reoperative valve surgery. Ann Thorac Surg 56:15-21.nDürrleman N, Pelerin M, Bouchard D, et al. 2004. Prosthetic valve thrombosis: Twenty year experience at the Montreal Heart Institute. J Thorac Cardiovasc Surg 127:1388-92.nHorstkotte D, Burckhardt D. 1992. Prosthetic valve thrombosis. J Heart Valve Dis 4:141-53.nHuseybe DG, Pluth JR, Piehler JM, et al. 1983. Reoperation on prosthetic heart valves: an analysis of risk factors in 552 patients. J Thorac Cardiovasc Surg 86:543-52.nLytle BW, Cosgrove DM, Taylor PC, et al. 1986. Reoperations for valve surgery:perioperative mortality and determinants of risk for 1000 patients, 1958-1984. Ann Thorac Surg 42:632-43.nRizeoli G, Guglielmi G, Toscano G, et al. 1999. Reoperations for acute prosthetic thrombosis and pannus: an assessment of rates, relationship and risk. Eur J Cardiothorac Surg 16:74-80.n