Fulminant <i>Neisseria meningitidis</i>: Role for Extracorporeal Membrane Oxygenation


  • Michael S. Firstenberg
  • Daniele Blais
  • Erik Abel
  • Louis B. Louis
  • Benjamin Sun
  • Julie E. Mangino




Invasive meningococcal disease is often associated with complications of septic shock and central nervous system dysfunction. Extracorporeal membrane oxygenation is more commonly being used for respiratory failure and sepsis, but neurologic injury and potential coagulopathy are often considered relative contraindications. We report a successful case of complicated Neisseria meningitidis septic shock with disseminated intravascular coagulopathy requiring extracorporeal support.


Bilukha OO, Rosenstein N. 2005. Prevention and control of meningococcal disease. Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep 54(RR-7):1-21.nFirstenberg MS, Abel E, Blais D, et al. The use of extra-corporeal membrane oxygenation for severe necrotizing soft tissue infections complicated by septic shock. Am Surg. In press.nKasirajan V, Smedira NG, McCarthy JF, Casselman F, Boparai N, McCarthy PM. 1999. Risk factors for intracranial hemorrhage in adults on extracorporeal membrane oxygenation. Eur J Cardiothorac Surg 15:508-14.nLewandowski K. 2000. Extracorporeal membrane oxygenation for severe acute respiratory failure. Crit Care 4:156-68.nPeek GJ, Mugford M, Tiruvoipati R, et al, for the CESAR trial collaboration. 2009. Efficacy and economic assessment of conventional ventilatory support versus extracorporeal membrane oxygenation for severe adult respiratory failure (CESAR): a multicentre randomised controlled trial. Lancet 374:1351-63.nSmedira NS, Moazami D, Golding CM, et al. 2001. Clinical experience with 202 adults receiving extracorporeal membrane oxygenation for cardiac failure: survival at five years. J Thorac Cardiovasc Surg 122:92-102.nStephens DS, Greenwood B, Brandtzaeg P. 2007. Epidemic meningitis, meningococcaemia, and Neisseria meningitidis. Lancet 369:2196-210.n



How to Cite

Firstenberg, M. S., Blais, D., Abel, E., Louis, L. B., Sun, B., & Mangino, J. E. (2010). Fulminant <i>Neisseria meningitidis</i>: Role for Extracorporeal Membrane Oxygenation. The Heart Surgery Forum, 13(6), E376-E378. https://doi.org/10.1532/HSF98.20101072