Quadruple Valve Replacement with Mechanical Valves: An 11-Year Follow-up Study

Authors

  • Yukun Cao
  • Chunhu Gu
  • Guocheng Sun
  • Shiqiang Yu
  • Hongbing Wang
  • Dinghua Yi

DOI:

https://doi.org/10.1532/HSF98.20111124

Abstract

Background: We performed the first quadruple valve replacement with mechanical valves, combined with the correction of complex congenital heart disease on November 17, 1999. We report here the 11-year follow-up study.

Methods: A 47-year-old man with subacute rheumatic endocarditis, a ventricular septal defect, and an obstruction of the right ventricular outflow tract required replacement of the aortic, mitral, tricuspid, and pulmonary valves; repair of the ventricular septal defect; and relief of the obstruction of the right ventricular outflow tract. The surgery was done on November 17, 1999, after careful systemic preparation of the patient. Warfarin therapy with a target international normalized ratio (INR) range of 1.5 to 2.0 was used. Follow-up included monitoring the INR, recording the incidences of thromboembolic and bleeding events, electrocardiography, radiography, and echocardiography evaluations.

Results: The patient's INR was maintained between 1.5 and 2.0. All 4 mechanical prosthetic heart valves worked well. He is in generally good health without any thromboembolic or bleeding complications.

Conclusions: Long-term management is challenging for patients who have experienced quadruple valve replacement with mechanical valves; however, promising results could mean that replacement of all 4 heart valves in 1 operation is feasible in patients with quadruple valve disease, and an INR of 1.5 to 2.0 could be appropriate for Chinese patients with undergoing valve replacement with mechanical valves.

References

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Published

2012-06-14

How to Cite

Cao, Y., Gu, C., Sun, G., Yu, S., Wang, H., & Yi, D. (2012). Quadruple Valve Replacement with Mechanical Valves: An 11-Year Follow-up Study. The Heart Surgery Forum, 15(3), E145-E149. https://doi.org/10.1532/HSF98.20111124

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