The Impact of Diabetes on Acute Kidney Injury After Off-Pump Coronary Artery Bypass Grafting

Diabetes Associated with AKI after Off-pump CABG

Authors

  • Ruhua Shen, MD Department of Cardiovascular Surgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China
  • Yang Wang, MSc Department of Cardiovascular Surgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China
  • Bing Zhang, PhD Department of Cardiovascular Surgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China
  • Jianjun Ge, PhD Department of Cardiovascular Surgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China

DOI:

https://doi.org/10.1532/hsf.4885

Keywords:

Diabetes, Off-pump coronary artery bypass grafting, Acute kidney injury, Risk factor

Abstract

Background: Acute kidney injury (AKI) is one of the most frequent complications after coronary artery bypass grafting. Previous studies have shown that diabetes is a key pathogenic factor. But how diabetes is related to AKI in off-pump CABG patients still is in debate. Here, we aim to study the relationship between diabetes and AKI after off-pump coronary artery bypass grafting (off-pump CABG).

Methods: Patients who underwent off-pump CABG from April 2017 to December 2020 in The First Affiliated Hospital of USTC were enrolled in this retrospective study. AKI was defined and classified, according to the criteria proposed by the Acute Kidney Injury Network. The incidence risk of acute kidney injury was measured by logistic regression and compared.

Results: A total of 395 patients, who underwent off-pump CABG, were included in this study. The postoperative acute kidney injury rate for a patient with diabetes was significantly higher than for patients without diabetes (x2 = 5.09, P = 0.024). Logistic regression analysis showed that patients with diabetes have a much higher risk with acute kidney injury occurring after off-pump coronary artery bypass grafting (OR 1.852, 95% CI 1.161 - 2.954, P = 0.01).

Conclusions: Diabetes is an independent risk factor for postoperative AKI for patients undergoing off-pump CABG.

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Published

2022-09-12

How to Cite

Shen, R., Wang, Y., Zhang, B., & Ge, J. (2022). The Impact of Diabetes on Acute Kidney Injury After Off-Pump Coronary Artery Bypass Grafting: Diabetes Associated with AKI after Off-pump CABG. The Heart Surgery Forum, 25(5), E660-E664. https://doi.org/10.1532/hsf.4885

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Articles