Transcatheter Aortic Valve Implantation and Simultaneous Closure of Ostium Secundum Atrial Septal Defect


  • Miralem Pasic
  • Felix Berger
  • Giuseppe D'Ancona
  • Stephan Dreysse
  • Semih Buz
  • Thorsten Drews
  • Roland Hetzer
  • Axel Unbehaun
  • Marian Kukucka



We were faced with a difficult question: how to treat a high-risk patient with severe aortic valve stenosis and a secundum atrial septal defect (ASD II). An 85-year-old woman with progressive dyspnea and pedal edema and in New York Heart Association class IV was treated with concomitant transapical aortic valve implantation and transcatheter closure of the ASD II. The combined procedure and postoperative course were completely uneventful. At 2 years after the clinical follow-up, the patient is doing well. This case report demonstrates, for the first time, the feasibility, safety, and effectiveness of simultaneous application of 2 transcatheter methods—aortic valve implantation and closure of an ASD II. As surgeons, we should consider percutaneous treatment of combined structural heart disease in patients at high risk for conventional surgery.


Berger F, Ewert P, Bjornstad PG, et al. 1999. Transcatheter closure as standard treatment for most interatrial defects: experience in 200 patients treated with the Amplatzer Septal Occluder. Cardiol Young 9:468-73.nKing TD, Thompson SL, Steiner C, Mills NL. 1976. Secundum atrial septal defects. Nonoperative closure during cardiac catheterization. JAMA 235:2506-9.nPasic M, Dreysse S, Drews T, et al. 2010. Improved technique of transapical aortic valve implantation: "the Berlin addition." Ann Thorac Surg 89:2058-60.nPasic M, Unbehaun A, Dreysse S, et al. 2010. Transapical aortic valve implantation in 175 consecutive patients: excellent outcome in very highrisk patients. J Am Coll Cardiol 56:813-20.n



How to Cite

Pasic, M., Berger, F., D’Ancona, G., Dreysse, S., Buz, S., Drews, T., Hetzer, R., Unbehaun, A., & Kukucka, M. (2011). Transcatheter Aortic Valve Implantation and Simultaneous Closure of Ostium Secundum Atrial Septal Defect. The Heart Surgery Forum, 14(6), E354-E356.




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