Complete Revascularization Showed A Better Cardiac Function Improvement In Patients With Low Ejection Fraction

Authors

  • Tri Wisesa Soetisna, MD, PhD, MHA Department of Cardiothoracic and Vascular Surgery, National Cardiovascular Centre Harapan Kita, Jakarta, Indonesia https://orcid.org/0000-0002-7428-3600
  • Wiraga Adi Nugraha, MD Department of Cardiothoracic and Vascular Surgery, National Cardiovascular Centre Harapan Kita, Jakarta, Indonesia https://orcid.org/0000-0002-2295-4628
  • Fitri Setyani Rokim, MD Department of Cardiothoracic and Vascular Surgery, National Cardiovascular Centre Harapan Kita, Jakarta, Indonesia
  • Lisca Namretta, MD Department of Cardiothoracic and Vascular Surgery, National Cardiovascular Centre Harapan Kita, Jakarta, Indonesia
  • Muhammad Bagus Ronidipta Pradana, MD Department of Cardiothoracic and Vascular Surgery, National Cardiovascular Centre Harapan Kita, Jakarta, Indonesia
  • Digjaya Utama, MD, PhD Department of Cardiothoracic and Vascular Surgery, National Cardiovascular Centre Harapan Kita, Jakarta, Indonesia

DOI:

https://doi.org/10.1532/hsf.4123

Keywords:

Coronary artery bypass grafting, revascularization, cardiac function, ejection fraction, systolic dysfunction

Abstract

Purpose: This study aimed to compare postoperative ejection fraction (EF) in response to coronary artery bypass grafting (CABG) among patients with preoperative EF <35% and >35%.

Methods: A retrospective study was conducted in a single institution using clinical data of 660 patients undergoing elective on-pump CABG in 2018-2019. Patients were classified into two groups based on preoperative left ventricle ejection fraction (<35% and >35%). The primary endpoint was the change of postoperative ejection fraction.

Results: In this study, 72 patients had preoperative left ventricle ejection fraction <35% (group A) while the other 588 patients had ejection fraction >35% (group B). Among both groups, the duration of cardiopulmonary bypass (CPB) and aortic clamp (AxC) were not significantly different (P > 0.05). The transformation of pre- and postoperative EF in groups A and B was significantly different (2.91+10.31 vs. -0.14+4.57, P < 0.001). There was a significant difference in the duration of ICU stay (73.42+112.55 vs. 34.43+64.99, P < 0.001) and postoperative ventilatory support (25.54+43.92 vs. 16.42+45.87, P < 0.008) between group A and B.

Conclusion: Low preoperative EF showed better improvement in cardiac function after surgery. We concluded that the result could be affected by revascularization of hibernating myocardium. 

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Published

2022-05-31

How to Cite

Soetisna, T. W., Nugraha, W. A., Rokim, F. S., Namretta, L., Pradana, M. B. R., & Utama, D. (2022). Complete Revascularization Showed A Better Cardiac Function Improvement In Patients With Low Ejection Fraction. The Heart Surgery Forum, 25(3), E425-E428. https://doi.org/10.1532/hsf.4123

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Articles