Comparison of Demographic Profile, Laboratory, Epidemiology and Clinical Outcomes in Patients with Native Valve and Prosthetic Valve Endocarditis

Comparison of Native Valve and Prosthetic Valve Endocarditis

Authors

  • Hulya Yilmaz Ak Istanbul University-Cerrahpasa, Cardiology Institute, Department of Anesthesiology and Reanimation, Istanbul, Turkey
  • Yasemin Ozsahin Istanbul University-Cerrahpasa, Cardiology Institute, Department of Anesthesiology and Reanimation, Istanbul, Turkey
  • Mehmet Ali Yesiltas Istanbul Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Department of Cardiovascular Surgery, Istanbul, Turkey
  • Ismail Haberal Istanbul University-Cerrahpasa, Cardiology Institute, Department of Cardiovascular Surgery, Istanbul, Turkey
  • Serkan Kahraman University of Health Sciences Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Department of Cardiovascular Surgery, Istanbul, Turkey
  • Dogac Oksen Siirt Kurtalan State Hospital, Department of Cardiology, Siirt, Turkey
  • Mustafa Yildiz Istanbul University-Cerrahpasa, Cardiology Institute, Department of Cardiology, Istanbul, Turkey

DOI:

https://doi.org/10.1532/hsf.3715

Keywords:

infective endocarditis, native valve endocarditis, prosthetic valve endocarditis

Abstract

Background: Infective endocarditis (IE) is a heterogenous infection that affects the endothelial surface of the intracardiac structures and other implanted intracardiac devices. We aimed to compare demographical characteristics, causative microorganisms, treatment, and prognosis of prosthetic and native valve endocarditis diagnosed in two separate hospitals.

Material and methods: Between 2010 and 2020, patients admitted with the diagnosis of IE were retrospectively included in our multicenter study. Patients' demographic and epidemiological data, clinical characteristics, infected intracardiac structure and sort of valve, culprit microorganisms, laboratory findings, treatment manifestations and in-hospital outcomes with a period of 6 months were obtained from an electronic medical record system.

Results: A total of 173 consecutive patients had diagnosed IE, 60.1% (104 patients) of them native valve endocarditis (NVE) and 39.8 % (69 patients) of them prosthetic valve endocarditis (PVE).  Baseline demographic properties were not different except hypertension and atrial fibrillation. Patients with prior hypertension were 25% (26 patients) in NVE; 39.1% (27 patients) in PVE and the difference was statistically significant. Septic shock was significantly higher in the PVE group than the NVE group (7.4% versus 1%;
P = .036), and also recurrent endocarditis occurred more frequently in the PVE group than the NVE group (8.8% versus 1%; P = .016).

Conclusion: In our study, although we detected higher mean age, HT, RDW and atrial fibrillation rates compared with NVE, we did not detect a significant difference in mortality and morbidity.

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Published

2021-06-11

How to Cite

YILMAZ AK, H., ÖZŞAHİN, Y., YESILTAS, M. A., HABERAL, İsmail, KAHRAMAN, S., OKSEN, D., & YILDIZ, M. (2021). Comparison of Demographic Profile, Laboratory, Epidemiology and Clinical Outcomes in Patients with Native Valve and Prosthetic Valve Endocarditis: Comparison of Native Valve and Prosthetic Valve Endocarditis. The Heart Surgery Forum, 24(3), E534-E543. https://doi.org/10.1532/hsf.3715

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