Atypical Takotsubo Cardiomyopathy With Persistent Left Ventricular Aneurysm After Cardiac Surgery


  • Xiaojie Zhang Zhejiang University School of Medicine, Sir Run Run Shaw Hospital, Zhejiang, China



Takotsubo cardiomyopathy, caridiac surgery, complication, prognosis


A 57-year-old man was admitted to the hospital because of severe mitral regurgitation. Minimally invasive mitral valvuloplasty was performed. Six months after surgery, he presented with discomfort. Urgent coronary angiography showed a normal coronary artery and large left ventricular aneurysm. After atypical Takotsubo cardiomyopathy was diagnosed, his clinical symptoms and heart function were improved with medication for his persistent left ventricular aneurysm. After 24 hours, Hotler showed a lethal ventricular arrhythmia.
Surgical treatment was recommended and refused. After four years of observation, he died of asystole. Takotsubo cardiomyopathy is considered a severe complication after surgery. The prognosis is very poor if it has catastrophic complications.


Chiariello GA, Bruno P, Colizzi C, Crea F, Massetti M. 2016. Takotsubo Cardiomyopathy Following Cardiac Surgery. J Card Surg. Feb;31(2):89-95.

Del Buono MG, O’Quinn MP, Garcia P, et al. 2017. Cardiac arrest due to ventricular fibrillation in a 23-year old woman with broken heart syndrome. Cardiovasc Pathol. 30:78–81.

Itoh H, Miyake Y, Hioki I, et al. 2007. Report of Takotsubo cardiomyopathy occurring during cardiopulmonary by- pass. J Extra Corpor Technol. 39:109–111.

Jesel L, Berthon C, Messas N, Lim HS, Girardey M, Marzak H, Marchandot B, Trinh A, Ohlmann P, Morel O. 2018. Ventricular arrhythmias and sudden cardiac arrest in Takotsubo cardiomyopathy: Incidence, predictive factors, and clinical implications. Heart Rhythm. 15(8):1171-1178.

Kudaiberdiev T, Akhmedova I, Imanalieva G, Abdildaev I, Jooshev K, Ashimov J, Mirzabekov A, Gaybildaev J. 2017. Surgical treatment of left ventricular wall rupture, regarded as a consequence of Takotsubo cardiomyopathy. SAGE Open Med Case Rep. Jan 18;5:2050313X16689210.

Lyon AR, Bossone E, Schneider B, et al. 2016. Current state of knowledge on Takotsubo syndrome: a position statement from the taskforce on Takotsubo syndrome of the Heart Failure Association of the European Society of Cardiology. Eur J Heart Fail. 18:8–27.

Miyata M, Nakazato K, Sakamoto N, et al. 2013. Left ventricular plasty improved cardiac function in a case of takotsubo cardiomyopathy with persistent aneurysm. J Cardiol Cases. 7:133–136.

Rodrigues LB, Batista A, Monteiro F, et al. 2015. ST-segment elevation during general anesthesia for non-cardiac surgery: A case of takotsubo. Rev Bras Anestesiol. 65:403–406.

Syed FF, Asirvatham SJ, Francis J. 2011. Arrhythmia occurrence with takotsubo cardiomyopathy: A literature review. Europace. 13:780–788.

Templin C, Ghadri JR, Diekmann J, et al. 2015. Clinical features and outcomes of takotsubo (stress) cardiomyopathy. N Engl J Med. 373:929–938.

Wong CP, Jim MH, Chau EM, et al. 2008. Iatrogenic Tako-Tsubo cardiomyopathy. Int J Cardiol. 125:16–18.



How to Cite

Zhang, X. (2021). Atypical Takotsubo Cardiomyopathy With Persistent Left Ventricular Aneurysm After Cardiac Surgery. The Heart Surgery Forum, 24(3), E442-E444.