Left Atrial Mechanical Function Predicts Postoperative AF in Patients with Rheumatic Mitral Valve Disease Who Underwent Mitral Valve Surgery

Authors

  • Yan Jin, MD Department of Cardiovascular Surgery, General Hospital of Northern Theater Command, Liaoning, China
  • Yang Wang Department of Cardiovascular Surgery, General Hospital of Northern Theater Command, Liaoning, China
  • Jian Zhang, MD Department of Cardiovascular Surgery, General Hospital of Northern Theater Command, Liaoning, China
  • Fengjie Yue, MM Department of Cardiovascular Surgery, General Hospital of Northern Theater Command, Liaoning, China
  • Zongtao Yin, MD Department of Cardiovascular Surgery, General Hospital of Northern Theater Command, Liaoning, China
  • Yan Zhu, MD Department of Cardiovascular Surgery, General Hospital of Northern Theater Command, Liaoning, China
  • Yan Yu, MD Department of Cardiovascular Surgery, General Hospital of Northern Theater Command, Liaoning, China
  • Huishan Wang, MD, PhD Department of Cardiovascular Surgery, General Hospital of Northern Theater Command, Liaoning, China

DOI:

https://doi.org/10.1532/hsf.3343

Keywords:

Acute kidney injury, Coronary artery bypass surgery, Hyperchloremia, Propensity score matching

Abstract

Objective: Postoperative atrial fibrillation (PoAF) is a common complication after surgical mitral valve replacement. Late PoAF is independently associated with long-term mortality. This study aimed to test the utility of preoperative left atrial mechanical function as a predictor of early and late PoAF in clinical practice.

Methods: Patients (N = 150) with a rheumatic mitral valve who underwent mitral valve replacement with or without tricuspid valvuloplasty and who were in stable sinus rhythm were included. Baseline characteristics and transthoracic echocardiographic assessment information on the day before surgery were collected. Em, Em´, and Ei´ indicate early diastolic peak velocity of the mitral valve, early diastolic velocity at the lateral wall of the mitral annulus, and early diastolic velocity at the interventricular septal annulus, respectively.

Results: Early PoAF was present in 59 of 150 patients (39.3%), and 32 of 150 patients (21.3%) developed late PoAF within 1 year after surgery. Among all of the variables examined, age, diabetes, early mitral filling velocity (Mitral E), left atrial mechanical function (Mitral A), Em/Em´, Em/Ei´, and mitral transvalvular gradient showed a significant correlation with PoAF. Only age, Mitral A, and mitral transvalvular gradient showed strong, significant correlations with the occurrence of late PoAF. In a multivariate analysis, predictors of late PoAF recurrence included early PoAF and Mitral A.

Conclusion: Routine evaluation of Mitral A is feasible and useful to predict early and late PoAF in patients with a rheumatic mitral valve undergoing surgical mitral valve replacement.

References

Akilli H, Aribas A, Icli A, et al. Predictive value of transmitral A-wave acceleration time for paroxysmal atrial fibrillation. Echocardiography 2019;36:1633-1638.

Damiano RJ, Jr., Schwartz FH, Bailey MS, et al. The Cox maze IV procedure: Predictors of late recurrence. J Thorac Cardiovasc Surg 2011;141:113-121.

Delgado V, Di Biase L, Leung M, et al. Structure and function of the left atrium and left atrial appendage: AF and stroke implications. J Am Coll Cardiol 2017;70:3157-3172.

El-Chami MF, Kilgo P, Thourani V, et al. New-onset atrial fibrillation predicts long-term mortality after coronary artery bypass graft. J Am Coll Cardiol 2010;55:1370-1376.

Jin Y, Wang HS, Wang ZW, et al. Risk factors for midterm cardiac function deterioration after valve replacement surgery in patients with rheumatic mitral stenosis. J Card Fail 2013;19:565-570.

Joint Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology (ESC), European Association for Cardio-Thoracic Surgery (EACTS), Vahanian A, et al. Guidelines on the management of valvular heart disease (version 2012). Eur Heart J 2012;33:2451-2496.

Kawamoto N, Fujita T, Fukushima S, et al. Late onset of atrial fibrillation in patients undergoing mitral valve repair for type II dysfunction. J Cardiol 2018;71:346-351.

Lanters EAH, Teuwen CP, Yaksh A, et al. Intraoperative inducibility of atrial fibrillation does not predict early postoperative atrial fibrillation. J Am Heart Assoc 2018;7.

Lee SH, Kang DR, Uhm JS, et al. New-onset atrial fibrillation predicts long-term newly developed atrial fibrillation after coronary artery bypass graft. Am Heart J 2014;167:593-600.e1.

Magruder JT, Collica S, Belmustakov S, et al. Predictors of late-onset atrial fibrillation following isolated mitral valve repairs in patients with preserved ejection fraction. J Card Surg 2016;31:486-492.

Mathew JP, Fontes ML, Tudor IC, et al. A multicenter risk index for atrial fibrillation after cardiac surgery. JAMA 2004;291:1720-1729.

Mottram PM, Marwick TH. Assessment of diastolic function: What the general cardiologist needs to know. Heart 2005;91:681-695.

Nagueh SF, Appleton CP, Gillebert TC, et al. Recommendations for the evaluation of left ventricular diastolic function by echocardiography. J Am Soc Echocardiogr 2009;22:107-133.

Nishimura RA, Otto CM, Bonow RO, et al. 2014 AHA/ACC guideline for the management of patients with valvular heart disease: Executive summary: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 2014;63:2438-2488.

Park YM, Cha MS, Park CH, et al. Newly developed post-operative atrial fibrillation is associated with an increased risk of late recurrence of atrial fibrillation in patients who underwent open heart surgery: Long-term follow up. Cardiol J 2017;24:633-641.

Park-Hansen J, Greve AM, Clausen J, et al. New-onset of postoperative atrial fibrillation is likely to recur in the absence of other triggers. Ther Clin Risk Manag 2018;14:1641-1647.

Pathan F, Sivaraj E, Negishi K, et al. Use of atrial strain to predict atrial fibrillation after cerebral ischemia. JACC Cardiovasc Imaging 2018;11:1557-1565.

Rudski LG, Lai WW, Afilalo J, et al. Guidelines for the echocardiographic assessment of the right heart in adults: a report from the American Society of Echocardiography endorsed by the European Association of Echocardiography, a registered branch of the European Society of Cardiology, and the Canadian Society of Echocardiography. J Am Soc Echocardiogr 2010;23:685-713.

Wang H, Han J, Wang Z, et al. A prospective randomized trial of the cut-and-sew Maze procedure in patients undergoing surgery for rheumatic mitral valve disease. J Thorac Cardiovasc Surg 2018;155:608-617.

Wang H, Han J, Wang Z, et al. Efficacy of cut-and-sew surgical ablation for atrial fibrillation in patients with giant left atria undergoing mitral valve surgery: A propensity-matched analysis. Semin Thorac Cardiovasc Surg 2019;31:796-802.

Wijffels MC, Kirchhof CJ, Dorland R, et al. Atrial fibrillation begets atrial fibrillation. A study in awake chronically instrumented goats. Circulation 1995;92:1954-1968.

Xu S, Zhang J, Xu YL, et al. Relationship between angiotensin converting enzyme, apelin, and new-onset atrial fibrillation after off-pump coronary artery bypass grafting. Biomed Res Int 2017;2017:7951793.

Zhang J, Xu S, Xu Y, et al. Relation of mitochondrial DNA copy number in peripheral blood to postoperative atrial fibrillation after isolated off-pump coronary artery bypass grafting. Am J Cardiol 2017;119:473-477.

Zhang J, Xu Y, Xu S, Liu Y, Yu L, Li Z, Xue X, Wang H. Plasma circular RNAs, Hsa_circRNA_025016, predict postoperative atrial fibrillation after isolated off-pump coronary artery bypass grafting. J Am Heart Assoc 2018;7:e006642.

Published

2020-12-17

How to Cite

Jin, Y., Wang, Y., Zhang, J., Yue, F., Yin, Z., Zhu, Y., Yu, Y., & Wang, H. (2020). Left Atrial Mechanical Function Predicts Postoperative AF in Patients with Rheumatic Mitral Valve Disease Who Underwent Mitral Valve Surgery. The Heart Surgery Forum, 23(6), E907-E912. https://doi.org/10.1532/hsf.3343

Issue

Section

Article