Inflammatory Response after Different Ablation Strategies for Paroxysmal Atrial Fibrillation


  • Guangli Yin Department of Cardiology, the Second Hospital of Hebei Medical University, Shijiazhuang, China
  • Bofei Ma Department of Cardiology, the Second Hospital of Hebei Medical University, Shijiazhuang, China
  • Bolun Zhou Xiangya School of Medicine, Central South University, Changsha, China
  • Jinglan Wu Department of Cardiology, the Second Hospital of Hebei Medical University, Shijiazhuang 050000, China
  • Ling You Department of Cardiology, the Second Hospital of Hebei Medical University, Shijiazhuang, China
  • Ruiqin Xie Department of Cardiology, the Second Hospital of Hebei Medical University, Shijiazhuang, China



paroxysmal atrial fibrillation; catheter ablation; inflammation; recurrence of atrial fibrillation


Background: Catheter ablation for atrial fibrillation (AF) has been gaining popularity; however, the trend of inflammatory response markers in patients treated with different catheter ablation strategies over time and their predictability of AF recurrence remain unknown.

Methods: A total of 210 patients with AF were enrolled and grouped according to surgical mode as follows: freeze group, RF group, and freeze3D group. The subjects were tested for related indexes before and after surgery. To determine AF recurrence during follow up, 24-h ambulatory electrocardiography was performed at two, three, six, and 12 months after surgery.

Results: The inflammation indexes of the three groups peaked between one and three days after surgery but fell at different time points (P < .05). The recurrence rate of paroxysmal atrial fibrillation (PAF) was positively correlated with the increase in the percentage of white blood cells and neutrophils after surgery (P < .05).

Conclusions: The postoperative inflammation indices peaked and fell at different time points after different catheter ablation methods. In addition, the recurrence rate of AF in patients treated with freeze3D is lower.


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How to Cite

Yin, G. ., Ma, B. ., Zhou, B. ., Wu, J. ., You, L. ., & Xie, R. (2020). Inflammatory Response after Different Ablation Strategies for Paroxysmal Atrial Fibrillation. The Heart Surgery Forum, 23(5), E703-E711.