Primary Cardiac Amyloidosis Mimicking Interstitial Lung Disease and Bleeding Diathesis: A Case Report


  • Hamza Duygu
  • Azem Akilli
  • Filiz Ozerkan
  • Mehdi Zoghi
  • Mustafa Akin
  • Cem Nazli
  • Oktay Ergene



Primary amyloidosis is a rare systemic disease due to various organ involvements that can lead to atypical clinical findings. In this article, we discuss a case of primary cardiac amyloidosis in a patient presenting with bleeding eyelids and interstitial lung disease.


Cueto-Garcia L, Reeder GS, Kyle RA, et al. 1985. Echocardiographic findings in systemic amyloidosis: spectrum of cardiac involvement and relation to survival. J Am Coll Cardiol 6:737-43.nDubrey SW, Cha K, Anderson J, et al. 1998. The clinical features of immunoglobulin light-chain (AL) amyloidosis with heart involvement QJM 91:141-57.nDubrey S, Falk R. 1995. Amyloidosis and the heart. Br J Cardiol 7:193-9.nFalk RH, Plehn JF, Deering T, et al. 1987. Sensitivity and specificity of the echocardiographic features of cardiac amyloidosis. Am J Cardiol 59:418-22.nGertz MA, Lacy MQ, Dispenzieri A. 1999. Amyloidosis: recognition, confirmation, prognosis, and therapy. Mayo Clin Proc 74:490-4.nGrogan M, Gertz MA, Kyle RA, et al. 2000. Five or more years of survival in patients with primary systemic amyloidosis and biopsy-proven cardiac involvement. Am J Cardiol 85:664-5.nLanda G, Aloni E, Milshtein A. 2004. Eyelid bleeding and atypical amyloidosis. Am J Ophthalmol 138:495-6.nSkinner M, Sanchorawala V, Seldin DC, et al. 2004. High-dose melphalan and autologous stem-cell transplantation in patients with AL amyloidosis: an 8-year study. Ann Intern Med 140:85-93.nSueyoshi E, Sakamoto I, Okimoto T, et al. 2006. Cardiac amyloidosis: typical imaging findings and diffuse myocardial damage demonstrated by delayed contrast-enhanced MRI. Cardiovasc Intervent Radiol 29:710-2.n



How to Cite

Duygu, H., Akilli, A., Ozerkan, F., Zoghi, M., Akin, M., Nazli, C., & Ergene, O. (2007). Primary Cardiac Amyloidosis Mimicking Interstitial Lung Disease and Bleeding Diathesis: A Case Report. The Heart Surgery Forum, 10(3), E177-E179.