Impact of Controlling Nutritional Status Score (CONUT) and Prognostic Nutritional Index (PIN) on Patients Undergoing Coronary Artery Bypass Graft Surgery

  • Melike Elif Teker Açıkel Department of Cardiovascular Surgery, Haseki Training and Research Hospital, Istanbul, Turkey
  • Ali Kubilay Korkut Department of Cardiovascular Surgery, Haliç University, Istanbul, Turkey https://orcid.org/0000-0001-7282-3725
Keywords: Coronary Artery By-pass Graft Surgery, CONUT, PIN

Abstract

Background: The aim of this study is to evaluate the negative effect of malnutrition in patients with coronary artery disease who are undergoing coronary artery bypass graft surgery.

Methods: In this study, we analyzed 149 patients, who underwent coronary artery bypass surgery. Nutritional status of the patients was classified using controlling nutritional status score (CONUT) and prognostic nutritional index (PNI). Statistical correlation between malnutrition and complication following operation was evaluated with the chi-square test. Statistical alpha significant level was accepted P < 0.05.

Results: There were various complications in 38 patients. Renal failure was the predominant problem in 18 of them. There was statistical significance between malnutrition and complication (P < .001). There were more complications in the controlling nutritional status score and prognostic nutritional index groups. Renal complication (P < .001), hemorrhage (P < .05), and mortality (P < .05) were high in the severe controlling nutritional status score and prognostic nutritional index groups.

Conclusion: There are manifest correlations between the severe controlling nutritional status score and prognostic nutritional index groups and morbidity and mortality after coronary artery bypass graft surgery. We found that renal complications, hemorrhage, and mortality rate

References

Arbel Y, Finkelstein A, Halkin A, Birati EY, Revivo M, Zuzut M et.al. 2012. Neutrophil/lymphocyte ratio is related to the severity of coronary artery disease and clinical outcome in patients undergoing angiography. Atherosclerosis 225 (2); 456-460.

Cederhdm J, Jagren C, Hellström K. 1993. Nutritional status and performance capacity in internal medicine patients. Clin Nutr 12: 8-14.

Joles JA, Willekes-Koolschijn N, Koomans HA. 1997. Hypoalbuminemia causes high blood viscosity by increasing red cell lysophosphatidylcholine. Kidney international 52; 761-770.

Kalantar-Zadeh K, Block G, Horwich T, Fonarow G.C. 2004. Reverse epidemiology of conventional cardiovascular risk factors in patients with chronic heart failure. J American College of Cardiology. 43; 1439-1444.

Kamath SK, Lawler M, Smith AE, Kalat T, Olson R. 1986. Hospital malnutrition: a 33-hospital screening study. J Am Diet Assoc 86: 203-206.

Keskin M, Ipek G, Aldag M, Altay S, Hayiroglu MI, Borklu EB, et.al. 2017. Effect of nutritional status on mortality in patients undergoing coronary artery bypass grafting. Nutrition. 48: 82-86.

Maalej N, Albrecht R, Loscalzo J, Folts JD. 1999. The potent platelet inhibitory effects of S-nitrosated albumin coating of artificial surface. Journal of the American College of Cardiology 33; 1408-1414.

Oduncu V, Erkol A, Karabay C, Kurt M, Akgün T, Bulut M. et.al. 2013. The prognostic value of serum albumin levels on admission in patients with acute ST-segment elevation myocardial infarction undergoing a primary percutaneous coronary intervention. Coronary artery disease. 24 (2); 88-94.

Onsrud M, Thorsby E. 1981. Influence of in vivo hydrocortisone on some human blood lymphocyte subpopulations. I. Effect on natural killer cell activity. Scandinavian journal of immunology 13 (6); 573-579.

Pu J, Mintz GS, Brilakis ES, Banerjee S, Abdel-Karim AR, Maini B et.al. 2012. In vivo characterization of coronary palques: novel findings from comparing greyscale and virtual histology intravascular ultrasound and near-infrared spectroscopy. European Heart Journal. 33 (3); 372-383.

Sargento L, Longo S, Lousanda N, dos Reis R.P. 2014. The importance of assessing nutritional status in elderly patients with heart failure. Current heart failure reports. 11; 220-226.

Taggart DP, Thomas BF. 2006. Coronary artery bypass grafting is still the best treatment for multivessel and left main disease, but patients need to know. Ann Thorac Surg 82: 1966-1975.

Van Venrooji LM, van Leeuwen PA, de Vos R, Borgmeijer-Hoelen MM, de Mol BA. 2008. Postoperative protein and energy intake and postoperative complications in well-nourished, non-hospitalized elderly cardiac surgery patients. Clin Nutr 27: 117-121.

Wada H, Dohi T, Miyauchi K, Doi S, Konishi H, Naito R, et.al. 2017. Prognostic impact of nutritional status assessed by the controlling nutritional status score in patients with stable coronary artery disease undergoing percutaneous coronary intervention. Clin. Res. Cardiol 106: 875-883.

Wada H, Dohi T, Miyauchi K, Jun S, Endo H, Doi S, et.al. 2018. Relationship between the prognostic nutritional index and long-term clinical outcomes in patients with stable coronary artery disease. J. Cardiol. 72 (2): 155-161.

Published
2019-07-25
How to Cite
Teker Açıkel, M., & Korkut, A. (2019). Impact of Controlling Nutritional Status Score (CONUT) and Prognostic Nutritional Index (PIN) on Patients Undergoing Coronary Artery Bypass Graft Surgery. The Heart Surgery Forum, 22(4), E294-E297. https://doi.org/10.1532/hsf.2493
Section
Articles