Simultaneous Pulmonary Embolism and Ischemic Stroke in a Patient with Cor Biloculare after Glenn Anastomosis

  • Sipei Pan Department of Neurology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China
  • Zhangyang Wang Department of Neurology, Huashan Hospital, Fudan University, Shanghai, China
  • Xiang Wei Department of Neurology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China
  • Hai Tang Department of Neurology, the Affiliated Hospital of Xuzhou Medical University, Xuzhou, China
  • Zhengzheng Li Department of Neurology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China
  • Yang Zhang Department of Neurology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China
  • Saijun Zhou Department of Neurology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China
  • Nan Zhang Department of Neurology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China
Keywords: Cor biloculare, Glenn anastomosis, thrombosis

Abstract

Background: Cor biloculare, two-chambered heart due to the absence of atrial and ventricular septa, is a rare congenital heart anomaly. For Cor biloculare and other cardiac defects with single ventricle physiology, Glenn anastomosis has been developed as a palliative procedure. Thrombosis secondary to Glenn anastomosis in the patient with Cor biloculare could pose a serious threat to the survival, and has never been reported before.

Case report: We report the case of a 27-year-old patient, with past history of Glenn anastomosis that was performed 7 years ago for the palliation of Cor biloculare. She presented with pulmonary embolism and ischemic stroke simultaneously at 7 days after Cesarean section. Due to her critical status, systemic anticoagulation with low-molecular-weight heparin was started immediately, followed by lifelong warfarin therapy. Pulmonary embolism regressed and neurological symptoms were considerably diminished after the anticoagulation treatment.

Conclusion: This case illuminates the potential risk of thrombotic events in this patient cohort and demonstrates that anticoagulation therapy is an effective, secure, and appropriate for the management of this disease.

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Published
2019-05-08
How to Cite
Pan, S., Wang, Z., Wei, X., Tang, H., Li, Z., Zhang, Y., Zhou, S., & Zhang, N. (2019). Simultaneous Pulmonary Embolism and Ischemic Stroke in a Patient with Cor Biloculare after Glenn Anastomosis. The Heart Surgery Forum, 22(3), E180-E182. https://doi.org/10.1532/hsf.2054
Section
Articles