Hemolysis Combined with Renal Injury after Mitral Valve Repair
Keywords:hemolysis, renal injury, mitral valve repair, complication
Hemolysis combined with renal injury is a rare but serious complication after mitral valve repair. Here, we report two representative cases of hemolysis combined with renal injury. Although timely reoperation was not possible for several reasons, different clinical outcomes were observed that could aid in future decisions.
Abourjaili G, Torbey E, Alsaghir T, et al. 2012. Hemolytic anemia following mitral valve repair: A case presentation and literature review. Exp Clin Cardiol, 17:248-50.
Cardoso C, Cachado P, Garcia T. 2013. Hemolytic anemia after mitral valve repair: a case report. BMC Res Notes, 6:165
Concepcion B, Korbet SM, Schwartz MM. 2008. Intravascular hemolysis and acute renal failure after mitral and aortic valve repair. Am J Kidney Dis 52:1010-5.
Dutra FF, Alves LS, Rodrigues D, et al. 2014. Hemolysis-induced lethality involves inflammasome activation by heme. Proc Natl Acad Sci USA 111:E4110-8.
Gungunes A, Akpinar I, Dogan M, et al. 2010. Do all hemolytic anemias that occur after mitral valve repair require surgical treatment? Clin Cardiol 33:E76-8.
Hayes C, Shafi H, Mason H, et al. 2015. Successful reduction of plasma free-hemoglobin using therapeutic plasma exchange: A case report. Transfus Apher Sci 54: 253-5.
Khalighi MA, Henriksen KJ, Chang A, et al. 2015. Intratubular hemoglobin casts in hemolysis-associated acute kidney injury. Am J Kidney Dis 65:337-41.
Lam BK, Cosgrove DM, Bhudia SK, et al. 2004. Hemolysis after mitral valve repair: mechanisms and treatment. Ann Thorac Surg 77:191-5.
Rother RP, Bell L, Hillmen P, et al. 2005.The clinical sequelae of intravascular hemolysis and extracellular plasma hemoglobin: a novel mechanism of human disease. JAMA 293:1653-62.
Schaer DJ, Vinchi F, Ingoglia G, et al. 2014. Haptoglobin, hemopexin, and related defense pathways-basic science, clinical perspectives, and drug development. Front Physiol 5:415.
Shih HM, Chen YC, Pan CF, et al. 2013. Hemolysis-induced acute kidney injury following cardiac surgery: a case report and review of the literature. Hemodial Int 17:101-6.
Viaene E, Schroeyers P, Dujardin K. 2013. Haemolysis and acute renal failure after mitral valve repair. Acta Cardiol 68:189-91.
Yeo TC, Freeman WK, Schaff HV, et al. 1998. Mechanisms of hemolysis after mitral valve repair: assessment by serial echocardiography. J Am Coll Cardiol 32: 717-23.