Urine Output during Cardiopulmonary Bypass Predicts Acute Kidney Injury after Coronary Artery Bypass Grafting

  • Mehmet Yilmaz Department of Anesthesiology and Reanimation, Derince Research and Education Hospital Kocaeli
  • Rezan Aksoy Department Cardiovascular Surgery, Derince Research and Education Hospital Kocaeli
  • Vildan Kilic Yilmaz Anesthesiology and Reanimation Department, Kocaeli State Hospital, Kocaeli
  • Canan Balci Department of Anesthesiology and Reanimation, Derince Research and Education Hospital Kocaeli
  • Cagri Duzyol Department of Anesthesiology and Reanimation, Derince Research and Education Hospital Kocaeli
  • Atike Tekeli Kunt Department of Anesthesiology and Reanimation, Derince Research and Education Hospital Kocaeli


Objective: This study evaluated the relationship between the amount of urinary output during cardiopulmonary bypass and acute kidney injury in the postoperative period of coronary artery bypass grafting.
Methods: Two hundred patients with normal preoperative serum creatinine levels, operated on with isolated CABG between 2012-2014 were investigated retrospectively. The RIFLE (Risk, injury, failure, loss of function, and end-stage renal disease) risk scores were calculated for each patient in the third postoperative day. Patients were distributed into two groups in relation to the presence of acute kidney injury or not and these two groups were compared.
Results: The urinary output (mL/kg/hour) during cardiopulmonary bypass in the acute kidney injury negative group was significantly higher than in the acute kidney injury positive group (P = .022). In case of a urinary output value 3.70 and lower to predict acute kidney injury positivity, sensitivity was detected as 71.43%. Results of the analysis for urinary output predict positivity of acute kidney injury.
Conclusion: We suggest that urine output during cardiopulmonary bypass is a significant criteria that could predict acute kidney injury following coronary artery bypass grafting with cardiopulmonary bypass. Attempts to increase the urine output during cardiopulmonary bypass could help to maintain the renal functions during and after surgery.


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