Pharmacomechanical Thrombectomy for Acute Symptomatic Lower Extremity Deep Venous Thrombosis

Authors

  • Eyup Serhat Calik Department of Cardiovascular Surgery, Erzurum Regional Training and Research Hospital, Erzurum
  • Ozgur Dag Department of Cardiovascular Surgery, Erzurum Regional Training and Research Hospital, Erzurum
  • Mehmet Ali Kaygin Department of Cardiovascular Surgery, Erzurum Regional Training and Research Hospital, Erzurum
  • Oruc Alper Onk Department of Cardiovascular Surgery, Erzurum Regional Training and Research Hospital, Erzurum
  • Bilgehan Erkut Department of Cardiovascular Surgery, Erzincan University Medical Faculty, Erzincan

DOI:

https://doi.org/10.1532/hsf.1366

Abstract

Background: The purpose of this study was to evaluate the efficacy and safety of pharmacomechanical thrombectomy performed by using a rotational thrombectomy device for the treatment of deep vein thrombosis.
Methods: Between April 2012 and November 2014, 17 patients with acute deep vein thrombosis underwent pharmacomechanical thrombolysis. The thrombectomy device was used in a single-session technique for patients with lower-extremity deep vein thrombosis. After the procedure, the effect of thrombolysis was evaluated in 3 grades venographically. Grade I showed lysis of under 50%, and grade III showed complete lysis.
Results: Ten patients (58.8%) had an iliofemoral thrombosis and 7 (41.2%) had a femoropopliteal venous thrombosis. At the end of the pharmacomechanical thrombectomy procedure, 12 patients (70%) had complete (grade III) thrombus resolution. Grade I and II lysis were noted in 2 (12%) and 3 (18%) patients, respectively. Additionally, four (23.5%) required an additional lytic infusion as a result of residual thrombi. The overall grade III, II, and I thrombus resolution rates, including the supplemental thrombolysis, were 82.2% (n = 14), 12% (n = 2), and 5.8% (n = 1), respectively. There was no mortality.
Conclusion: Based on the present data, use of the Cleaner thrombectomy device may prove to be a safe and feasible single-session pharmacomechanical thrombectomy method for the treatment of acute deep vein thrombosis. To prove the effectiveness of this type treatment, a more extensive large-scale studies are needed.

Published

2015-08-30

How to Cite

Calik, E. S., Dag, O., Kaygin, M. A., Onk, O. A., & Erkut, B. (2015). Pharmacomechanical Thrombectomy for Acute Symptomatic Lower Extremity Deep Venous Thrombosis. The Heart Surgery Forum, 18(4), E178-E183. https://doi.org/10.1532/hsf.1366

Issue

Section

Articles

Most read articles by the same author(s)

1 2 > >>