Surgical Treatment of Intracardiac-Extending Intravenous Leiomyomatosis: A Single Center Experience

Authors

  • Yang Li Department of Cardiovascular Surgery, General Hospital of Beijing Military Region, Beijing
  • Nan Yang Department of Stomatology, 309th Hospital of PLA, Beijing
  • Long Lu Department of Cardiovascular Surgery, General Hospital of Beijing Military Region, Beijing
  • Fengxia Ma Department of Cardiovascular Surgery, General Hospital of Beijing Military Region, Beijing
  • Jianmin Yao Department of Cardiovascular Surgery, General Hospital of Beijing Military Region, Beijing

DOI:

https://doi.org/10.1532/hsf.1362

Abstract

Background: Few data were known on surgical management of intracardiac-extending in patients with intravenous leiomyomatosis (IVL).
Methods: From June 2007 to December 2014, six women (mean age, 39.3 ± 7.5 years; range, 24-55 years) with intracardiac-extending IVL were treated surgically at our hospital. Data were obtained from medical and pathological records, including characteristics of patients, surgical management, and follow-up.
Results: Surgery was performed successfully in all patients. Of 6 patients, 4 underwent one-stage operation and 2 underwent two-stage procedures. Circulatory arrest with hypothermia was used for a cardiotomy combined with venotomy in
5 patients. Complete resection was done in 5 patients. There were no perioperative deaths or complications in any of the patients. Hospital stay was 11.2 ± 2.9 days (range 7-15 days). All patients were followed-up for a mean of 41.0 ± 19.1 months (range, 17-69 months) after surgery. A recurrence of pelvic mass was found in 1 patient, but no symptoms or intravenous mass were reported. No obstruction occurred in any patient with a venotomy.
Conclusion: Surgery is a better therapy for IVL and complete removal has favorable outcomes.

References

Filsoufi F, Farivar RS, Anderson C, Santerre D, Adams DH. 2002. Renal vein injury complicating removal of intravenous leiomyoma. J Thorac Cardiovasc Surg 123:820-2.

Gehr NR, Lund O, Alstrup P, Nielsen JS, Villadsen AB, Bartholdy NJ. 1999. Recurrence of uterine intravenous leiomyomatosis with intracardiac extension. Diagnostic considerations and surgical removal. Scand Cardiovasc J 33:312-14.

Guo X, Zhang C, Fang L, et al. 2011. Echocardiographic characteristics of intravenous leiomyomatosis with intracardiac extension: A single-institution experience. Echocardiography 28:934-40.

Larzon T, Friberg O, Lund P, Eliasson K, Agren G, Arbeus M. 2006. Intracardiac leiomyomatosis--a benign tumor with possible fatal outcome. Radical surgery for the safest result. Lakartidningen 103:2220-2.

Mandelbaum I, Pauletto FJ, Nasser WK. 1974. Resection of a leiomyoma of the inferior vena cava that produced tricuspid valvular obstruction. J Thorac Cardiovasc Surg 67:561-7.

Morice P, Chapelier A, Dartevelle P, Castaigne D, Lhomme C. 2001. Late intracaval and intracardiac leiomyomatosis following hysterectomy for benign myomas treated by surgery and gnrh agonist. Gynecol Oncol 83:422-3.

Nam MS, Jeon MJ, Kim YT, Kim JW, Park KH, Hong YS. 2003. Pelvic leiomyomatosis with intracaval and intracardiac extension: A case report and review of the literature. Gynecol Oncol 89:175-80.

Schindler N, Babrowski T, DeSai T, Alexander JC. 2012. Resection of intracaval leiomyomatosis using abdominal approach and venovenous bypass. Ann Vasc Surg 26:109 e107-111.

Yu L, Shi E, Gu T, Xiu Z, Fang Q, Wang C. 2011. Intravenous leiomyomatosis with intracardiac extension: A report of two cases. J Card Surg 26:56-60.

Zhang C, Miao Q, Liu X, et al. 2010. Intravenous leiomyomatosis with intracardiac extension. Ann Thorac Surg 89:1641-3.

Published

2016-05-09

How to Cite

Li, Y., Yang, N., Lu, L., Ma, F., & Yao, J. (2016). Surgical Treatment of Intracardiac-Extending Intravenous Leiomyomatosis: A Single Center Experience. The Heart Surgery Forum, 19(3), E094-E096. https://doi.org/10.1532/hsf.1362

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