Inflammatory Responses and CNS Injury: Implications, Prophylaxis, and Treatment
Berger C, Schabitz WR, Georgiadis D, Steiner T, Aschoff A, Schwab S. 2002. Effects of hypothermia on excitatory amino acids and metabolism in stroke patients: a microdialysis study. Stroke 33:519-24.nChapot R, Houdart E, Rogopoulos A, Mounayer C, Saint-Maurice JP, Merland JJ. 2002. Thromboaspiration in the basilar artery: report of two cases. AJNR Am J Neuroradiol 23:282-4.nColman RW. 1990. Platelet and neutrophil activation in cardiopulmonary bypass. Ann Thorac Surg 49:32-4.ndel Zoppo GJ, Schmid-Schonbein GW, Mori E, Copeland BR, Chang CM. 1991. Polymorphonuclear leukocytes occlude capillaries following middle cerebral artery occlusion and reperfusion in baboons. Stroke 22:1276-83.nDery O, Corvera CU, Steinhoff M, Bunnett NW. 1998. Proteinase-activated receptors: novel mechanisms of signaling by serine proteases. Am JPhysiol 274:C1429-52.nDietrich WD, Busto R, Valdes I, Loor Y. 1990. Effects of normothermic versus mild hyperthermic forebrain ischemia in rats. Stroke 21:1318-25.nDroghetti L, Giganti M, Memmo A, Zatelli R. 2002. Air embolism: diagnosis with single-photon emission tomography and successful hyperbaric oxygen therapy. Br J Anaesth 89:775-8.nHeinel LA, Rubin S, Rosenwasser RH, Vasthare US, Tuma RF. 1994. Leukocyte involvement in cerebral infarct generation after ischemia and reperfusion. Brain Res Bull 34:137-41.nHill GE, Alonso A, Spurzem JR, et al. 1995. Aprotinin and methylprednisolone equally blunt cardiopulmonary bypass-induced inflammation in humans. J Thorac Cardiovasc Surg 110:1658-62.nKim Y, Busto R, Dietrich WD, Kraydieh S, Ginsberg MD. 1996. Delayed postischemic hyperthermia in awake rats worsens the histopathological outcome of transient focal cerebral ischemia. Stroke 27:2274-80.nKrieger DW, De Georgia MA, Abou-Chebl A, et al. 2001. Cooling for acute ischemic brain damage (cool aid): an open pilot study of induced hypothermia in acute ischemic stroke. Stroke 32:1847-54.nLord RA, Roath OS, Thompson JE, et al. 1992. Effect of aprotinin on neutrophil function after major vascular surgery. Br J Surg 79:517-21.nMangano DT, Multicenter Study of Perioperative Ischemia Research Group. 2002. Aspirin and mortality from coronary bypass surgery. N Engl J Med 347:1309-17.nSmith PK, Muhlbaier LH. 1996. Aprotinin: safe and effective only with the full-dose regimen. Ann Thorac Surg 62:1575-7.nStriggow F, Riek-Burchardt M, Kiesel A, et al. 2001. Four different types of protease-activated receptors are widely expressed in the brain and are up-regulated in hippocampus by severe ischemia. Eur J Neurosci 14:595-608.nSuo Z, Wu M, Ameenuddin S, et al. 2002. Participation of protease-activated receptor-1 in thrombin-induced microglial activation. J Neurochem 80:655-66.nTilton RG, Berens KL. 2002. Functional role for selectins in the pathogenesis of cerebral ischemia. Drug News Perspect 15:351-7.nUra M, Sakato R, Nakayama Y, et al. 2000. Ultrasonic demonstration of manipulation-related aortic injuries after cardiac surgery. J Am Coll Cardiol 35:1303-10.nWang GJ, Deng HY, Maier CM, Sun GH, Yenari MA. 2002. Mild hypothermia reduces ICAM-1 expression, neutrophil infiltration and microglia/monocyte accumulation following experimental stroke. Neuroscience 114:1081-90.nWhitten CW, Latson TH, Allison PM, et al. 1992. Does aprotinin inhibit cardiopulmonary bypass-induced inflammation? [abstract] Anesthesiology 77:A266.nYano T, Anraku S, Nakayama R, Ushijima K. 2003. Neuroprotective effect of urinary trypsin inhibitor against focal cerebral ischemia-reperfusion injury in rats. Anesthesiology 98:465-73.nYano T, Anraku S, Nakayama R, Ushijima K. 2003. Neuroprotective effect of urinary trypsin inhibitor against focal cerebral ischemia-reperfusion injury in rats. Anesthesiology 98:465-73.nAsimakopoulis G, Thompson R, Nourshargh S, et al. 2000. An anti-inflammatory property of aprotinin discovered at the level of leukocyte extravasation. J Thorac Cardiovasc Surg 120:361-9.nAzzimondi G, Bassein L, Nonino F, et al. 1995. Fever in acute stroke worsens prognosis. A prospective study. Stroke 26:2040-3.nMoazami N, Smedira NG, McCarthy PM, et al. 2001. Safety and efficacy of intraarterial thrombolysis for perioperative stroke after cardiac operation. Ann Thorac Surg 72:1933-7.nMurkin JM. 1997. Cardiopulmonary bypass and the inflammatory response: a role for serine protease inhibitors? J Cardiothorac Vasc Anesth 11:19-23.nMurkin JM, Maurer J, Niemcryk S. 2002. Full dose aprotinin administration is associated with a significant decrease in perioperative stroke in patients undergoing elective cardiac surgery: a meta-analysis. Ann Thorac Surg 73:S374.nNabavi DG, Kloska SP, Nam EM, et al. 2002. MOSAIC: multimodal stroke assessment using computed tomography: novel diagnostic approach for the prediction of infarction size and clinical outcome. Stroke 33:2819-26.nNathan HJ, Wells GA, Munson JL, Wozny D. 2001. Neuroprotective effect of mild hypothermia in patients undergoing coronary artery surgery with cardiopulmonary bypass: a randomized trial. Circulation 104(12 suppl 1):I85-91.nPoullis M, Manning R, Laffan M, Haskard DO, Taylor KM, Landis RC. 2000. The antithrombotic effect of aprotinin: actions mediated via the proteaseactivated receptor 1. J Thorac Cardiovasc Surg 120:370-8.n
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