TY - JOUR AU - SHIRASAKA, TOMONORI AU - Arayawudhikul, Nuttapon AU - Tantraworasin, Apichat AU - Chartrungsan, Angsu AU - Sakboon, Boonsap AU - Cheewinmethasiri, Jaroen AU - Kamiya, Hiroyuki PY - 2022/02/07 Y2 - 2024/03/28 TI - The Influence of Left Ventricular Dysfunction on The Early and Midterm Outcome in The Patients Undergoing Off Pump Coronary Artery Bypass Grafting Assessed by Propensity Matched Score Analysis: Off pump CABG for Low EF patient JF - The Heart Surgery Forum JA - HSF VL - 25 IS - 1 SE - DO - 10.1532/hsf.4311 UR - https://journal.hsforum.com/index.php/HSF/article/view/4311 SP - E101-E107 AB - <p class="p1"><span class="s1"><strong>Background</strong>: It still remains unclear the depth of influence of left ventricular dysfunction on the recovery of patients’ physical conditions in the early and midterm period following off-pump coronary artery bypass grafting (OPCAB).</span></p><p class="p1"><span class="s1"><strong>Methods</strong>: From April 2011 to May 2018, 851 patients underwent OPCAB in our center. All were grouped into two groups: Those whose ejection fraction (EF) was under 35% were defined as the Low EF group (<em>N</em> = 158) and those who maintained EF over 35% were defined as the Faired EF group (<em>N</em> = 693). Preoperatively, there was significant difference in NYHA class (<em>P</em> &lt; 0.001), CCS class (<em>P</em> = 0.038), level of creatinine (<em>P</em> &lt; 0.001), and rate of establishment of IABP (<em>P</em> &lt; 0.001).</span></p><p class="p1"><span class="s1"><strong>Results</strong>: Regarding all-cause death in the early postoperative period, low EF was a not a risk factor in patients (<em>P</em> = 0.52) or in the matched cohort (<em>P</em> = 0.398); however, in the midterm, it was a significant risk factor in patients (HR 2.07, <em>P</em> = 0.016) and in the matched cohort (HR 2.72, P = 0.029). Overall survival at 5 years in the Low EF group was significantly inferior to that of the Faired EF group in all (67.4±4.1% and 86.1±2.9%, <em>P</em> = 0.001) and in the matched cohort (66.5±6.4% vs. 86.5±4.5%, <em>P</em> = 0.008).</span></p><p class="p1"><span class="s1"><strong>Conclusion</strong>: OPCAB seems beneficial for patients with LV dysfunction considering the early outcome, however, low EF is a significant risk factor for overall death in the midterm period.</span></p> ER -