TY - JOUR AU - YILMAZ AK, Hülya AU - ÖZŞAHİN, Yasemin AU - YESILTAS, Mehmet Ali AU - HABERAL, İsmail AU - KAHRAMAN, Serkan AU - OKSEN, Dogac AU - YILDIZ, Mustafa PY - 2021/06/11 Y2 - 2024/03/29 TI - Comparison of Demographic Profile, Laboratory, Epidemiology and Clinical Outcomes in Patients with Native Valve and Prosthetic Valve Endocarditis: Comparison of Native Valve and Prosthetic Valve Endocarditis JF - The Heart Surgery Forum JA - HSF VL - 24 IS - 3 SE - DO - 10.1532/hsf.3715 UR - https://journal.hsforum.com/index.php/HSF/article/view/3715 SP - E534-E543 AB - <p class="p1"><span class="s1"><strong>Background:</strong> Infective endocarditis (IE) is a heterogenous infection that affects the endothelial surface of the intracardiac structures and other implanted intracardiac devices. We aimed to compare demographical characteristics, causative microorganisms, treatment, and prognosis of prosthetic and native valve endocarditis diagnosed in two separate hospitals.</span></p><p class="p1"><span class="s1"><strong>Material and methods:</strong> Between 2010 and 2020, patients admitted with the diagnosis of IE were retrospectively included in our multicenter study. Patients' demographic and epidemiological data, clinical characteristics, infected intracardiac structure and sort of valve, culprit microorganisms, laboratory findings, treatment manifestations and in-hospital outcomes with a period of 6 months were obtained from an electronic medical record system.</span></p><p class="p1"><span class="s1"><strong>Results:</strong> A total of 173 consecutive patients had diagnosed IE, 60.1% (104 patients) of them native valve endocarditis (NVE) and 39.8 % (69 patients) of them prosthetic valve endocarditis (PVE).<span class="Apple-converted-space">  </span>Baseline demographic properties were not different except hypertension and atrial fibrillation. Patients with prior hypertension were 25% (26 patients) in NVE; 39.1% (27 patients) in PVE and the difference was statistically significant. Septic shock was significantly higher in the PVE group than the NVE group (7.4% versus 1%; <br /><em>P</em> = .036), and also recurrent endocarditis occurred more frequently in the PVE group than the NVE group (8.8% versus 1%; <em>P</em> = .016).</span></p><p class="p1"><span class="s1"><strong>Conclusion:</strong> In our study, although we detected higher mean age, HT, RDW and atrial fibrillation rates compared with NVE, we did not detect a significant difference in mortality and morbidity.</span></p> ER -