TY - JOUR AU - Yu, Hua AU - Ma, Likun AU - Feng, Kefu AU - Chen, Hongwu AU - Hu, Hao PY - 2017/02/28 Y2 - 2024/03/29 TI - Clinical Application of Optical Coherence Tomography in Patients with Non-ST-Elevation Acute Coronary Syndrome Combined with Intermediate Lesions JF - The Heart Surgery Forum JA - HSF VL - 20 IS - 1 SE - DO - 10.1532/hsf.1447 UR - https://journal.hsforum.com/index.php/HSF/article/view/1447 SP - E032-E037 AB - <div class="Section1"><p class="p1"><span class="s1"><strong>Objective:</strong> This study aimed to evaluate the clinical significance and safety of optical coherence tomography (OCT) in patients with non-ST-elevation acute coronary syndrome (NSTEACS) combined with intermediate lesions.</span></p><p class="p1"><span class="s1"><strong>Methods:</strong> Sixty-five NSTEACS patients with intermediate lesions confirmed with coronary angiography at our department were included in this study. Among them, <br /> 33 patients received only standardized drug treatment (drug group) and the other 32 patients received percutaneous coronary intervention (PCI) according to the OCT examination based on drug treatment (OCT group). Major adverse cardiovascular events (MACEs), revascularization, success rate of OCT examination, related complications, and other patient situations in the two groups during hospitalization and the 12-month follow-up period were compared.</span></p><p class="p1"><strong>Results:</strong> No death or stroke occurred in either group during hospitalization and follow-up. In the drug treatment group, six patients experienced frequent angina, and five patients with acute myocardial infarction were rehospitalized and underwent PCI procedures. In the OCT group, although two patients underwent repeat revascularization, no additional acute myocardial infarction events occurred. There was a statistically significant difference between the two groups (P &lt; .01). All patients in the OCT group successfully completed the related vessel examination, and 24 patients underwent PCI procedures because of unstable plaque diagnosed with OCT.</p><p class="p1"><span class="s1"><strong>Conclusion:</strong> OCT-guided PCI is safe and effective for the treatment of patients with NSTEACS combined with intermediate lesions.</span></p></div> ER -