@article{Li_Sun_Cheng_Mei_Liao_Li_Yuan_2018, title={Analysis of Nosocomial Infections in Post–Cardiac Surgery Extracorporeal Membrane Oxygenation Support Therapy}, volume={21}, url={https://journal.hsforum.com/index.php/HSF/article/view/1789}, DOI={10.1532/hsf.1789}, abstractNote={<div class="Section1"> <p class="p1"><span class="s1"><strong>Objectives:</strong> This study aims to analyze the nosocomial infection factors in post–cardiac surgery extracorporeal membrane oxygenation (ECMO) supportive treatment (pCS-ECMO).</span></p> <p class="p1"><span class="s1"><strong>Methods:</strong> The clinical data of the pCS-ECMO patients who obtained nosocomial infections (NI) were collected and analyzed retrospectively. Among the 74 pCS-ECMO patients, 30 occurred with NI, accounting for 40.5%; a total of 38 pathogens were isolated, including 22 strains of Gram-negative bacteria (57.9%), 15 strains of Gram-positive bacteria (39.5%), and 1 fungus (2.6%).</span></p> <p class="p1"><span class="s1"><strong>Results:</strong> Multidrug-resistant strains were highly concentrated, among which <em>Acinetobacter baumannii</em> and various coagulase-negative staphylococci were the main types; NI was related to mechanical ventilation time, intensive care unit (ICU) residence, ECMO duration, and total hospital stay, and the differences were statistically significant (<em>P</em> &lt; .05). The binary logistic regression analysis indicated that ECMO duration was a potential independent risk factor (OR = 0.992, <em>P</em> = .045, 95.0% CI = 0.984-1.000).</span></p> <p class="p1"><span class="s1"><strong>Conclusions:</strong> There existed significant correlations between the secondary infections of pCS-ECMO and mechanical ventilation time, ICU residence, ECMO duration, and total hospital stay; therefore, hospitals should prepare appropriate preventive measures to reduce the incidence of ECMO secondary infections.</span></p> </div>}, number={5}, journal={The Heart Surgery Forum}, author={Li, Binfei and Sun, Geqin and Cheng, Zhou and Mei, Chuangchuang and Liao, Xiaozu and Li, Jianwei and Yuan, Yong}, year={2018}, month={Sep.}, pages={E387-E391} }