Analysis of Risk Factors for Recurrent Pneumothorax in Patients after Primary Spontaneous Pneumothorax Surgery: A Single-Center Retrospective Study
DOI:
https://doi.org/10.59958/hsf.7487Keywords:
risk factors, recurrent, pneumothoraxAbstract
Background: Recurrent pneumothorax is a prevalent issue following primary spontaneous pneumothorax (PSP) surgery. This study identifies risk factors for PSP recurrence after surgery. Methods: This study included participants who had undergone surgery for PSP at our hospital from February 2021 to February 2024. Relevant demographic, clinical, radiological, and laboratory data were collected for each participant, and statistical analysis was performed using SPSS 29.0 statistical software (SPSS Inc., Chicago, IL, USA). Chi-squared tests, t-tests, and binary logistic regression analysis were utilized to assess the associations between risk factors and the likelihood of pneumothorax recurrence. Results: A total of 100 participants who underwent surgery for PSP at a single center were included in the analysis. The participants were 18–39 years old, with 53 participants in the no recurrent pneumothorax group and 47 participants in the recurrent pneumothorax group. No significant differences in demographic and clinical characteristics were observed between the two groups. The binary logistic regression analysis showed that c-reactive protein (odds ratio (OR) = 2.144, p < 0.001), white blood cell count (OR = 2.493, p = 0.011), neutrophil-to-lymphocyte ratio (OR = 3.031, p < 0.001), and chest tube duration (OR = 9.716, p = 0.010) were independent risk factors for the recurrence of PSP. Conclusion: This study emphasizes the crucial role of postoperative inflammatory response in the recurrence of PSP. Clinicians should monitor and manage these inflammatory markers to optimize postoperative management strategies, reduce recurrence rates, and improve long-term patient outcomes.
References
Adekoya AO, Adekoya AO, Amosu LO, Olatunji AA, Olusola-Bello MA, Ashaolu OO. Primary spontaneous pneumothorax in a term neonate. African Health Sciences. 2022; 22: 178–181.
Ennis SL, Dobler CC. Conservative versus interventional treatment for spontaneous pneumothorax. Breathe (Sheffield, England). 2020; 16: 200171.
Gilday C, Odunayo A, Hespel AM. Spontaneous Pneumothorax: Management and Prognosis. Topics in Companion Animal Medicine. 2021; 45: 100582.
Gilday C, Odunayo A, Hespel AM. Spontaneous Pneumothorax: Pathophysiology, Clinical Presentation and Diagnosis. Topics in Companion Animal Medicine. 2021; 45: 100563.
Jouneau S, Vuillard C, Salé A, Bazin Y, Sohier L, Kerjouan M, et al. Outpatient management of primary spontaneous pneumothorax. Respiratory Medicine. 2021; 176: 106240.
Marquette CH. Primary spontaneous pneumothorax: We have time to get some fresh air…. Revue des Maladies Respiratoires. 2023; 40: 206–208. (In French)
Hung WT, Cheng YJ, Chen JS. Video-Assisted Thoracoscopic Surgery Lobectomy for Lung Cancer in Nonintubated Anesthesia. Thoracic Surgery Clinic. 2020; 30: 73–82.
Lin CW, Huang KY, Lin CH, Wang BY, Kor CT, Hou MH, et al. Video-Assisted Thoracoscopic Surgery in Community-Acquired Thoracic Empyema: Analysis of Risk Factors for Mortality. Surgical Infections. 2022; 23: 191–198.
Lu CW, Liu WD, Hsu HH, Wu UI, Jeng YM, Chen YC, et al. Video-assisted thoracoscopic surgery for primary pulmonary cryptococcosis. Journal of the Formosan Medical Association. 2022; 121: 2237–2247.
M Castro P, Lareiro S, Rei J, Miranda J, Neves F, Guerra M. Video-assisted thoracoscopic surgery without chest drain placement. Portuguese Journal of Cardiac Thoracic and Vascular Surgery. 2021; 28: 35–38.
Qaqish TR, Cox S, Carr R, Katlic M. Treatment of Pleural Effusions with Nonintubated Video-Assisted Thoracoscopic Surgery. Thoracic Surgery Clinics. 2020; 30: 25–32.
Wong A, Galiabovitch E, Bhagwat K. Management of primary spontaneous pneumothorax: a review. ANZ Journal of Surgery. 2019; 89: 303–308.
Fung S, Ashmawy H, Safi SA, Schauer M, Krieg A, Schauer A, et al. Effectiveness of Video-Assisted Thoracoscopic Surgery with Bullectomy and Partial Pleurectomy in the Treatment of Primary Spontaneous Pneumothorax-A Retrospective Long-Term Single-Center Analysis. Healthcare (Basel, Switzerland). 2022; 10: 410.
Hallifax RJ, McKeown E, Sivakumar P, Fairbairn I, Peter C, Leitch A, et al. Ambulatory management of primary spontaneous pneumothorax: an open-label, randomised controlled trial. Lancet (London, England). 2020; 396: 39–49.
Lieu N, Ngo P, Chennapragada SM, Fitzgerald DA, Karpelowsky J, Pandit C, et al. Update in management of paediatric primary spontaneous pneumothorax. Paediatric Respiratory Reviews. 2022; 41: 73–79.
Mei Z, Wang Q, Zhang Y, Liu P, Ge M, Du P, et al. Risk Factors for Recurrence after anal fistula surgery: A meta-analysis. International Journal of Surgery (London, England). 2019; 69: 153–164.
Kong SS, Hosterman T, Bhanusali N. Recurrent Pneumothorax in a Patient With Poorly Controlled Systemic Lupus Erythematosus: A Case Report and Review of the Literature. Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases. 2021; 27: e153–e155.
Lee YCG. Primary Spontaneous Pneumothorax: Treat the Patient, Not the X-Ray. American Journal of Respiratory and Critical Care Medicine. 2023; 207: 1416–1417.
Saricam M, Guven O, Ozkan B. Utilizing the lymphocyte-monocyte ratio in predicting the recurrence of spontaneous pneumothorax. Cirugia Y Cirujanos. 2023; 91: 725–729.
Saito Y, Suzuki Y, Demura R, Kawai H. The outcome and risk factors for recurrence and extended hospitalization of secondary spontaneous pneumothorax. Surgery Today. 2018; 48: 320–324.
Motono N, Mizoguchi T, Ishikawa M, Iwai S, Iijima Y, Uramoto H. Adhesion is a risk factor for postoperative recurrence of spontaneous pneumothorax. Journal of Thoracic Disease. 2023; 15: 6788–6795.
Miyahara E, Ueda D, Kawasaki Y, Ojima Y, Kimura A, Okumichi T. Polyglycolic acid mesh for preventing post-thoracoscopic bullectomy recurrence. Surgery Today. 2021; 51: 971–977.
Akboga SA, Gokce A, Hatipoglu M, Beyoglu MA, Inan K, Sezen AI, et al. The relationship between mortality and inflammatory markers and the systemic immune inflammatory index in patients in the intensive care unit with a pneumothorax as a complication of COVID-19 disease. Irish Journal of Medical Science. 2022; 191: 1931–1936.
Riveiro-Blanco V, Pou-Álvarez C, Ferreiro L, Toubes ME, Quiroga-Martínez J, Suárez-Antelo J, et al. Recurrence of primary spontaneous pneumothorax: Associated factors. Pulmonology. 2022; 28: 276–283.
Gaunt A, Martin-Ucar AE, Beggs L, Beggs D, Black EA, Duffy JP. Residual apical space following surgery for pneumothorax increases the risk of recurrence. European Journal of Cardio-thoracic Surgery: Official Journal of the European Association for Cardio-thoracic Surgery. 2008; 34: 169–173.
Chambers A, Scarci M. In patients with first-episode primary spontaneous pneumothorax is video-assisted thoracoscopic surgery superior to tube thoracostomy alone in terms of time to resolution of pneumothorax and incidence of recurrence? Interactive Cardiovascular and Thoracic Surgery. 2009; 9: 1003–1008.
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