Analysis of Risk Factors of Early Mortality After Pericardiectomy For Constrictive Pericarditis

Authors

  • Jing-bin Huang, MD Department of Cardiothoracic Surgery, The People’s Hospital of Guangxi Zhuang Autonomous Region, and Guangxi Academy of Medical Sciences, Nanning, Guangxi, China
  • Zhao-ke Wen, MD Department of Cardiothoracic Surgery, The People’s Hospital of Guangxi Zhuang Autonomous Region, and Guangxi Academy of Medical Sciences, Nanning, Guangxi, China
  • Jian-rong Yang, MD Department of Cardiothoracic Surgery, The People’s Hospital of Guangxi Zhuang Autonomous Region, and Guangxi Academy of Medical Sciences, Nanning, Guangxi, China
  • Jun-jun Li, MD Department of Cardiothoracic Surgery, The People’s Hospital of Guangxi Zhuang Autonomous Region, and Guangxi Academy of Medical Sciences, Nanning, Guangxi, China
  • Min Li, MD Department of Cardiothoracic Surgery, The People’s Hospital of Guangxi Zhuang Autonomous Region, and Guangxi Academy of Medical Sciences, Nanning, Guangxi, China
  • Chang-chao Lu, MD Department of Cardiothoracic Surgery, The People’s Hospital of Guangxi Zhuang Autonomous Region, and Guangxi Academy of Medical Sciences, Nanning, Guangxi, China
  • Da-ying Liang, MD Department of Cardiothoracic Surgery, Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine, Nanning, Guangxi, China
  • Cheng-xin Wei, MD Department of Cardiothoracic Surgery, The People’s Hospital of Liuzhou City, Liuzhou, Guangxi, China

DOI:

https://doi.org/10.1532/hsf.4329

Keywords:

Incomplete pericardial dissection, fluid overload, tuberculosis pericarditis, operative deaths, pericardiectomy

Abstract

Background: We aimed to investigate risk factors of early mortality following pericardiectomy.

Methods: This was a retrospective study of patients undergoing pericardiectomy between January 1994 and May 2021 at The People’s Hospital of Guangxi Zhuang Autonomous Region, Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine, and The People’s Hospital of Liuzhou City.

Results: This study included 826 patients, who were divided into two groups: group with operative deaths (N = 66) and group without operative deaths (N = 760). There were 66 operative deaths (66/826, 8.0%). The causes of operative deaths were multiorgan failure (86/826, 10.4%). Preoperative CVP (P < 0.001), chest drainage (P < 0.001), surgical duration (P < 0.001), fluid balance postoperative day D2 (P < 0.001), and tuberculosis pericarditis (P = 0.001) in group with operative deaths were significantly higher than those in group without operative deaths.

Univariate and multivariate analyses showed that factors associated with operative deaths include male (P < 0.001), age (P < 0.001), ICU retention time (P < 0.001), postoperative hospitalization time (P < 0.001), preoperative central venous pressure (P = 0.018), postoperative central venous pressure (P < 0.001), D0 fluid balance (P < 0.001), D2 fluid balance (P < 0.001), postoperative chest drainage (P = 0.029), surgical duration (P = 0.003), serum creatinine baseline (P = 0.002), serum creatinine 24h after surgery (P < 0.001), serum creatinine 48h after surgery (P < 0.001), blood lactate (P < 0.001), and tuberculosis pericarditis (P = 0.033).

Conclusion: In our study, incomplete pericardial dissection, fluid overload, and tuberculosis pericarditis are associated with operative deaths following pericardiectomy.

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Published

2022-01-17

How to Cite

Huang, J.- bin, Wen, . Z.- ke ., Yang, J.- rong ., Li , J.- jun ., Li , M. ., Lu, C.- chao, Liang, D.- ying ., & Wei, C.- xin . (2022). Analysis of Risk Factors of Early Mortality After Pericardiectomy For Constrictive Pericarditis. The Heart Surgery Forum, 25(1), E056-E064. https://doi.org/10.1532/hsf.4329

Issue

Vol. 25 No. 1 (2022)

Section

Articles

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