Primary Cardiac Fibroma: A Rising Giant in a Small Cavity—Size Does Matter

  • Beelke D'hondt
  • Filip Rega
  • Luc Mertens
  • Marc Gewillig
  • Bart Meyns

Abstract

We report the case of a 5-month-old girl who presented with cardiac failure due to a cardiac fibroma originating from the interventricular septum. We also include some remarks about the etiology and the most favorable therapeutic strategy for the disease.

References

Cope JT, Lindsey JH, Kron IL. 1994. Pediatric cardiac surgery. St Louis, Mo: Mosby.\nFurguson HL, Hawkins EP, Cooley LD. 1996. Infant cardiac fibroma with clonal t(1;9)(q32;q22) and review of benign fibrous tissue cytogenetics. Cancer Genet Cytogenet 87:34-7.\nGeipel A, Krapp M, Germer U, Becker R, Gembruch U. 2001. Perinatal diagnosis of cardiac tumours. Ultrasound Obstet Gynecol 17:17-21.\nGowdamarajan A, Michler RE. 2000. Therapy for primary cardiac tumours: Is there role for heart transplantation? Curr Opin Cardiol 15:121-6.\nHahn H, Wicking C, Zaphiropoulous PG, et al. 1996. Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome. Cell 85:841-51.\nIngham PW, Nystedt S, Nakano Y, et al. 2000. Patched represses the Hedgehog signalling pathway by promoting modification of the Smoothened protein. Curr Biol 10:1315-18.\nIsaacs H. Fetal and neonatal cardiac tumours. 2004. Pediatr Cardiol 25:252-73.\nPadallino MA, Basso C, Milanesi O, et al. 2005. Surgically treated primary cardiac tumours in early infancy and childhood. J Thorac Cardiovasc Surg 129:1358-63.\nBurke AP, Rosado-de-Christenson M, Templeton PA, Virmani R. 1994. Cardiac fibroma: clinicopathologic correlates and surgical treatment. J Thoracic Cardiovasc Surg 108:862-70.\n
Published
2008-06-26
How to Cite
D’hondt, B., Rega, F., Mertens, L., Gewillig, M., & Meyns, B. (2008). Primary Cardiac Fibroma: A Rising Giant in a Small Cavity—Size Does Matter. The Heart Surgery Forum, 11(3), E134-E136. https://doi.org/10.1532/HSF98.20081001
Section
Articles

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