Progress in Research of Asymptomatic Primary Mitral Regurgitation Examination Methods: A Review of Literature


  • Chen Ma Graduate School of Zunyi Medical University, Zunyi, Guizhou, China
  • Xie Fei Graduate School of Zunyi Medical University, Zunyi, Guizhou, China
  • Weihao Ding Graduate School of Zunyi Medical University, Zunyi, Guizhou, China
  • Zongwei Xiao Department of Cardio-Thoracic Surgery, Chengdu Second People's Hospital, Zunyi Medical University, Chengdu, Sichuan, China



primary mitral regurgitation, speckle tracking echocardiography, cardiac magnetic resonance, brain natriuretic peptide, exercise stress test


Mitral regurgitation (MR) is a common valvular heart disease, which can be classified into primary and secondary, according to the cause. Primary mitral regurgitation (PMR) is caused by rheumatic fever, degenerative changes, valve prolapse, etc. The appearance of clinical symptoms has always been the best indicator of surgical intervention in patients with severe PMR, but for asymptomatic patients, the best treatment has been controversial. The choice of follow-up observation or early surgery has different results in different randomized studies. Two-dimensional echocardiography is the most commonly used detection method for evaluating MR, but its evaluation of the degree of reflux may be inaccurate, and there are differences in the outcomes of patients with asymptomatic PMR. Recent studies have shown that three-dimensional echocardiography, cardiac magnetic resonance, speckle-tracking echocardiography, brain natriuretic peptide, and exercise stress test can optimize the timing of surgery for asymptomatic patients and judge the asymptomatic of PMR.


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How to Cite

Ma, C., Fei, X., Wei Hao, D., & Xiao, Z. W. . (2021). Progress in Research of Asymptomatic Primary Mitral Regurgitation Examination Methods: A Review of Literature. The Heart Surgery Forum, 24(1), E116-E120.