Survival of Patients with Primary Cardiac Tumors in an 11-Year Single Center Study

Survival of primary cardiac tumors

  • Aizezi Maimaitiaili Department of Cardiac Surgery, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, China
  • Wei-min Zhang Department of Cardiac Surgery, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, China
  • Yong-zhong Guo Department of Cardiac Surgery, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, China
  • Doshahar Elmaik Department of Cardiac Surgery, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, China
  • Nian-he Tang Department of Cardiac Surgery, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, China
  • Zong-gang Zhang Department of Cardiac Surgery, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, China

Abstract

Background: Primary cardiac tumors are rare, but few studies have examined the relationship between risk factors and the prognosis. The aim of this study was to provide a survival analysis and risk factors for mortality in patients with primary cardiac tumors.

Methods: We retrospectively enrolled 71 patients diagnosed with primary cardiac tumors from June 2006 to November 2017 in our hospital. Patients’ population characteristics, treatment information, pathology, and follow-up data were obtained and analyzed.

Results: Of the 71 patients, 60 cases were benign, and 11 cases were malignant. Sex, age, New York Heart Association classification, the percentage of peripheral embolism, and surgery had no significant difference between benign and malignant groups (P >.05), but the percentage of arrhythmia, leg edema, and mortality rate was higher in the malignant tumor group than in the benign tumor group (P <.05). Compared with the benign tumor group, the percentage of biatrial lesions in the malignant tumor group was significantly higher (P <.05). Moreover, Independent risk factors included the treatment choice, pathology type, and number of tumor lesions (P <.05).

Conclusion: Our study suggests that conservative therapy, malignant cardiac tumor, and biatrial tumor lesion are independent risk factors for poor prognosis.

References

Bakaeen FG, Reardon MJ, Coselli JS, et al. 2003. Surgical outcome in 85 patients with primary cardiac tumors. Am J Surg 186(6):641-7; discussion 647.

Barnes H, Conaglen P, Russell P, Newcomb A. 2014. Clinicopathological and surgical experience with primary cardiac tumors. Asian Cardiovasc Thorac Ann 22(9):1054-8.

Barreiro M, Renilla A, Jimenez JM, et al. 2013. Primary cardiac tumors: 32 years of experience from a Spanish tertiary surgical center. Cardiovasc Pathol 22(6):424-7.

Bossert T, Gummert JF, Battellini R, et al. 2005. Surgical experience with 77 primary cardiac tumors. Interact Cardiovasc Thorac Surg 4(4):311-5.

Butany J, Nair V, Naseemuddin A, Nair GM, Catton C, Yau T. 2005. Cardiac tumours: diagnosis and management. Lancet Oncol 6(4):219-28.

Chitwood WR Jr. 1992. Clarence Crafoord and the first successful resection of a cardiac myxoma. Ann Thorac Surg 54(5):997-8.

Dias RR, Fernandes F, Ramires FJA, Mady C, Albuquerque CP, Jatene FB. 2014. Mortality and embolic potential of cardiac tumors = Mortalidade e potencial embólico dos tumores cardíacos. Arq Bras Cardiol 103(1):13-8. English, Portuguese.

Habertheuer A, Laufer G, Wiedemann D, et al. 2015. Primary cardiac tumors on the verge of oblivion: a European experience over 15 years. J Cardiothorac Surg 10:56.

Hoffmeier A, Sindermann JR, Scheld HH, Martens S. 2014. Cardiac tumors--diagnosis and surgical treatment. Dtsch Arztebl Int 111(12):205-11.

Kośmider A, Jaszewski R, Marcinkiewicz A, Bartczak K, Knopik J, Ostrowski S. 2013. 23-year experience on diagnosis and surgical treatment of benign and malignant cardiac tumors. Arch Med Sci 9(5):826-30.

Li S, Gao C. 2017. Surgical experience of primary cardiac tumor: single-institution 23-year report. Med Sci Monit 23:2111-7.

Mkalaluh S, Szczechowicz M, Torabi S, et al. 2017. Surgical treatment of cardiac tumors: insights from an 18-year single-center analysis. Med Sci Monit 23:6201-9.

Nomoto N, Tani T, Konda T, et al. 2017. Primary and metastatic cardiac tumors: echocardiographic diagnosis, treatment and prognosis in a 15-years single center study. J Cardiothorac Surg 12(1):103.

Oliveira GH, Al-Kindi SG, Hoimes C, Park SJ. 2015. Characteristics and survival of malignant cardiac tumors: a 40-year analysis of >500 patients. Circulation 132(25):2395-402.

Roberts WC. 1997. Primary and secondary neoplasms of the heart. Am J Cardiol 80(5): 671-82.

Saad AM, Abushouk AI, Al-Husseini MJ, et al. 2018. Characteristics, survival and incidence rates and trends of primary cardiac malignancies in the United States. Cardiovasc Pathol 33:27-31.

Simpson L, Kumar SK, Okuno SH, et al. 2008. Malignant primary cardiac tumors: review of a single institution experience. Cancer 112(11):2440-6.

Strecker T, Rösch J, Weyand M, Agaimy A. 2012. Primary and metastatic cardiac tumors: imaging characteristics, surgical treatment, and histopathological spectrum: a 10-year-experience at a German heart center. Cardiovasc Pathol 21(5):436-43.

Yin L, He D, Shen H, et al. 2016. Surgical treatment of cardiac tumors: a 5-year experience from a single cardiac center. J Thorac Dis 8(5):911-9.

Yu L, Gu T, Shi E, et al. 2014. Primary malignant cardiac tumors. J Cancer Res Clin Oncol 140(6):1047-55.

Published
2019-02-27
Section
Articles