Use of an On-X Prosthetic Valve In A 42-Year Old Female With Antiphospholipid Syndrome

Authors

  • Ayumi Koga Department of Cardiovascular Surgery, Kumamoto University Hospital, Kumamoto, Japan
  • Ken Okamoto Department of Cardiovascular Surgery, Kumamoto University Hospital, Kumamoto, Japan
  • Hirokazu Tazume Department of Cardiovascular Surgery, Kumamoto University Hospital, Kumamoto, Japan
  • Toshihiro Fukui

DOI:

https://doi.org/10.1532/hsf.1805

Keywords:

On-X valve, antiphospholipid syndrome, mitral valve

Abstract

Antiphospholipid syndrome is a rare autoimmune disease with a hypercoagulable state causing vascular thrombosis. We present the case of a 42-year old female who underwent mitral valve replacement with a mechanical valve 15 months ago. The postoperative course was uneventful, and echocardiography performed 14 months postoperatively showed good valve function. The patient developed sudden dyspnea 15 months postoperatively and was referred to our hospital. Echocardiography revealed mitral stenosis with stuck leaflets. Emergent re-mitral valve replacement was successfully performed using an On-X valve (On-X Life Technologies, Austin, TX, USA). The patient tested positive for antiphospholipid antibodies. Antiphospholipid syndrome should be considered when valve dysfunction occurs suddenly in relatively young female patients. The On-X valve may be considered as a therapeutic option in patients with antiphospholipid syndrome because of its low anticoagulation intensity.

References

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Erdogan D, Goren MT, Diz-Kucukkaya R, Inanc M. 2005. Assessment of cardiac structure and left atrial appendage functions in primary antiphospholipid syndrome: a transesophageal echocardiographic study. Stroke 36:592-596.

Karkar AM, Castresana MR, Odo N, Agarwal S. 2015. Anticoagulation dilemma in a high-risk patient with On-X valves. Ann Card Anaesth 18:257-260.

Miyakis S, LockshinMD, Atsumi T, et al. 2006. International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS). J Thromb Haemost 4:295-306.

Zuily S, Regnault V, Selton-Suty C, et al. 2011. Increased risk for heart valve disease associated with antiphospholipid antibodies in patients with systemic lupus erythematosus: meta-analysis of echocardiographic studies. Circulation 124:215-224.

Published

2018-01-31

How to Cite

Koga, A., Okamoto, K., Tazume, H., & Fukui, T. (2018). Use of an On-X Prosthetic Valve In A 42-Year Old Female With Antiphospholipid Syndrome. The Heart Surgery Forum, 21(1), E026-E027. https://doi.org/10.1532/hsf.1805

Issue

Section

Articles