Application of Autologous Blood Cell Salvage in Off-Pump Coronary Artery Bypass Graft Operation
DOI:
https://doi.org/10.1532/hsf.1609Abstract
Objective: To analyze whether application of autologous blood cell salvage can reduce the transfusion volume of allogeneic blood and complications of blood transfusion in off-pump coronary artery bypass operations.
Methods: We randomly divided 120 patients into autologous blood cell salvage group (experimental group, n = 60) and non-autologous blood cell salvage group (control group, n = 60). Volume of perioperative allogeneic blood transfusion of each patient was recorded. Moreover, complications and ICU retention times (H) of each patient were also recorded. The data were analyzed using t tests.
Results: The volume of allogeneic blood transfusion was significantly less in the experimental group than in the control group.
Conclusion: Application of autologous blood cell salvage in off-pump coronary artery bypass graft operation can reduce the volume of allogeneic blood transfusion, alleviate blood shortage, and reduce the incidence of postoperative complications, leading to medical, economic, and social benefits.
References
Adegoke AO, Akanni O, Dirisu J. 2011. Risk of transfusion-transmitted syphilis in a tertiary hospital in Nigeria. N Am J Med Sci 3:78-81.
Andreasen JJ, Dethlefsen C, Modrau IS, et al. 2011. Storage time of allogeneic red blood cells is associated with risk of severe postoperative infection after coronary artery bypass grafting. Eur J Cardiothorac Surg 39:329-34.
Cholette JM, Powers KS, Alfieris GM, et al. 2013. Transfusion of cell saver salvaged blood in neonates and infants undergoing open heart surgery significantly reduces RBC and coagulant product transfusions and donor exposures: results of a prospective, randomized, clinical trial. Pediatr Crit Care Med 14:137-47.
Jiang GQ, Bai DS, Chen P, et al. 2014. Modified laparoscopic splenectomy and azygoportal disconnection combined with cell salvage is feasible and might reduce the need for blood transfusion. World J Gastroenterol. 20:420-6.
Kuss O, von Salviati B, Börgermann J. 2010. Off-pump versus on-pump coronary artery bypass grafting: a systematic review and meta-analysis of propensity score analyses. Thorac Cardiovasc Surg 140:829-35.
Milne ME, Yazer MH, Waters JH, et al. 2015. Red blood cell salvage during obstetric hemorrhage. Obstet Gynecol.2015:919-23.
Ong LP, Thompson E, Sachdeva A, et al. 2016. Allogeneic blood transfusion in bilateral lung transplantation: impact on early Function and mortality. Eur J Cardiothorac Surg 49:668-74.
Saha KK, Deval M, Jagdale L, Sahani P. 2011. Off-pump coronary artery bypass grafting in a low-volume center. Heart Surg Forum 14:E349-53.
Scott AV, Nagababu E, Johnson DJ, et al. 2016. 2,3- diphosphoglycerate concentrations in autologous salvaged versus stored red blood cells and in surgical patients after transfusion. Anesth Analg 122:616-23.
Stone GW, Clayton TC, Mehran R, et al. 2012. Impact of major bleeding and blood transfusions after cardiac surgery: analysis from the Acute Catheterization and Urgent Intervention Triage strategy trial. Am Heart J 163:522-9.
Tan NL, Corbineau H, Phu BD, Verhoye JP. 2012. Is a cell saver necessary in off-pump coronary artery bypass surgery? Asian Cardiovasc Thorac Ann 20: 539-43.
Vassal O, Desgranges FP, Tosetti S, et al. 2016. Risk factors for intraoperative allogeneic blood transfusion during craniotomy for brain tumor removal in children. Paediatr Anaesth 26:199-206.
Vonk AB, Meesters MI, Garnier, et al. 2013. Intraoperative cell salvage is associated with reduced postoperative blood loss and transfusion requirements in cardiac surgery: a cohort study. Transfusion 53:2782-9.
