Impact of Preoperative Nesiritide on Renal Function after Mitral Valve Surgery

Authors

  • Sacha P. Salzberg
  • Maximillian Y. Emmert
  • Joseph Vassalotti
  • Deepa Rani Nandiwada
  • David H. Adams

DOI:

https://doi.org/10.1532/HSF98.20091025

Abstract

Nesiritide, a recombinant B-type natriuretic peptide used for the intravenous treatment of acute decompensated congestive heart failure. Concerns have been raised about the long-term use of nesiritide, but data is scarce regarding its use in acute congestive heart failure and during cardiac surgery. We conducted a retrospective data review to address the safety of nesiritide for pretreatment of patients undergoing mitral valve surgery

References

Cheng JW, Merl MY, Nguyen HM. 2005. Effect of nesiritide on renal function: a retrospective review. Curr Med Res Opin 21:1857-63.nDunavant S. 2002. Nesiritide vs nitroglycerin for decompensated congestive heart failure. JAMA 288:571-2; author reply 572-3.nSackner-Bernstein JD, Kowalski M, Fox M, Aaronson K. 2005. Short-term risk of death after treatment with nesiritide for decompensated heart failure: a pooled analysis of randomized controlled trials. JAMA 293:1900-5.nSalzberg SP, Filsoufi F, Anyanwu A, et al. 2005. High-risk mitral valve surgery: perioperative hemodynamic optimization with nesiritide (BNP). Ann Thorac Surg 80:502-6.nWang DJ, Dowling TC, Meadows D, et al. 2004. Nesiritide does not improve renal function in patients with chronic heart failure and worsening serum creatinine. Circulation 110:1620-5.n

Published

2009-08-14

How to Cite

Salzberg, S. P., Emmert, M. Y., Vassalotti, J., Nandiwada, D. R., & Adams, D. H. (2009). Impact of Preoperative Nesiritide on Renal Function after Mitral Valve Surgery. The Heart Surgery Forum, 12(4), E217-E218. https://doi.org/10.1532/HSF98.20091025

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